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Wen-Chun Kuo

Explore the profile of Wen-Chun Kuo including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 249
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Recent Articles
1.
Lin C, Tsai Y, Kao K, Lin C, Zhou S, Ho M, et al.
Eur J Med Res . 2023 Apr; 28(1):155. PMID: 37085944
Background: Positive fluid balance and tissue fluid accumulation are associated with adverse outcomes in sepsis. Vascular endothelial growth factor (VEGF) increases in sepsis, promotes vascular permeability, and may affect tissue...
2.
Liao J, Cheng Y, You S, Kuo W, Huang C, Chiou J, et al.
Brain Behav Immun . 2020 Aug; 90:26-46. PMID: 32739365
Evidence suggests that the Parkinson's disease (PD) pathogenesis is strongly associated with bidirectional pathways in the microbiota-gut-brain axis (MGBA), and psychobiotics may inhibit PD progression. We previously reported that the...
3.
Hsu S, Kuo W, Chen Y, Yen C, Chen Y, Chen K, et al.
Acta Biomater . 2013 Feb; 9(5):6606-15. PMID: 23376237
Nerve regeneration remains a difficult challenge due to the lack of safe and efficient matrix support. We designed a laminin (LN)-modified chitosan multi-walled nerve conduit combined with bone marrow stem...
4.
Huang Y, Hsu S, Kuo W, Chang-Chien C, Cheng H, Huang Y
J Biomed Mater Res A . 2011 Jul; 99(1):86-93. PMID: 21800418
This study assesses the ability and potential of carbon nanotube (CNT)/chitosan to guide axon re-growth after nerve injuries. The CNT/chitosan fibers were produced via the coagulation and hydrodynamic focusing method....
5.
Lin Y, Tsai M, Lo M, Chang S, Shih Y, Lee M, et al.
Neurosurgery . 2011 Jul; 70(2):479-89. PMID: 21796002
Background: Kringle 1-5 (K1-5) is a potent antiangiogenesis factor for treating breast cancer and hepatocellular carcinoma. However, its use in treating brain tumors has not been studied. Objective: To evaluate...
6.
Lin Y, Kuo H, Lo M, Tsai M, Lee M, Huang W, et al.
Restor Neurol Neurosci . 2011 Jun; 29(4):265-74. PMID: 21697592
Purpose: Nerve root traction injuries induce spinal cord inflammation and lead to neuronal death within days. In the present study, we examined the inflammatory response one week after multiple cervical...
7.
Huang W, Kuo H, Tsai M, Ma H, Chiu C, Huang M, et al.
J Gene Med . 2011 May; 13(5):283-9. PMID: 21557400
Background: Following spinal cord injury, the delivery of neurotrophic factors to the injured spinal cord has been shown to promote axonal regeneration and functional recovery. In previous studies, we showed...
8.
Kuo H, Tsai M, Huang M, Chiu C, Tsai C, Lee M, et al.
J Neurosci . 2011 Mar; 31(11):4137-47. PMID: 21411654
Spinal cord injury elicits an inflammatory response that recruits macrophages to the injured spinal cord. Quantitative real-time PCR results have shown that a repair strategy combining peripheral nerve grafts with...
9.
Tsai M, Chen Y, Weng C, Liou D, Yang H, Chen C, et al.
Ann N Y Acad Sci . 2010 Jul; 1199:194-203. PMID: 20633125
Glycine N-methyltransferase (GNMT) is the most abundant hepatic methyltransferase and plays important roles in regulating methyl group metabolism. In the central nervous system, GNMT expression is low and its function...
10.
Huang W, Kuo W, Hsu S, Cheng C, Liu J, Cheng H
Neurosci Lett . 2010 Jan; 472(2):79-84. PMID: 20079803
Chondroitin sulfate proteoglycan (CSPG) is a major component of glial scar to restrict axonal regeneration in the lesion site after spinal cord injury (SCI). Chondroitinase ABC (ChABC), a bacteria enzyme,...