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Wen-Cheng Su

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Citations 50
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Recent Articles
1.
Su W, Hung C, Wang Y, Peng H, Huang W, Lo Y, et al.
In Vivo . 2023 Oct; 37(6):2524-2532. PMID: 37905652
Background/aim: Autosomal dominant polycystic kidney disease (ADPKD) is a prevalent genetic disorder primarily caused by mutations in Pkd1 (PC1), which account for the majority of ADPKD cases. These mutations contribute...
2.
Chen Y, Su Y, Shieh G, Su B, Su W, Huang P, et al.
FASEB J . 2019 Oct; 33(11):13051-13061. PMID: 31589480
Polycystic kidney disease (PKD) is characterized by the expansion of fluid-filled cysts in the kidney, which impair the function of kidney and eventually leads to end-stage renal failure. It has...
3.
Weng C, Chung F, Chen Y, Lin S, Huang P, Kuo T, et al.
Sci Rep . 2016 Dec; 6():38894. PMID: 27966586
Observational studies have established a strong association between matrix metalloproteinase-9 (MMP-9) and ventricular arrhythmia. However, whether MMP-9 has a causal link to ventricular arrhythmia, as well as the underlying mechanism,...
4.
Liu W, Yang H, Su W, Wang C, Chen H, Wang H, et al.
PLoS One . 2012 Sep; 7(9):e43824. PMID: 22962590
Background/aims: Ribavirin significantly enhances the antiviral response of interferon-α (IFN-α) against Hepatitis C virus (HCV), but the underlying mechanisms remain poorly understood. Recently, p53 has been identified as an important...
5.
Su W, Liu W, Cheng C, Chou Y, Hung K, Huang W, et al.
FEBS Lett . 2009 Jul; 583(17):2793-8. PMID: 19619545
Cellular mechanisms involving the enhancement of interferon (IFN) signaling by ribavirin remain poorly understood. Here, we identified a novel role of ribavirin in the communication between p53 and the mammalian...
6.
Liu W, Su W, Cheng C, Hwang L, Wang C, Chen H, et al.
J Infect Dis . 2007 Jun; 196(3):425-34. PMID: 17597457
Background: Ribavirin's mechanism of action in the treatment of chronic hepatitis C remains to be clarified. Double-stranded RNA-activated protein kinase (PKR) plays a role in cell defense against virus infection....