Wen-Bing Chen
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Explore the profile of Wen-Bing Chen including associated specialties, affiliations and a list of published articles.
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24
Citations
222
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Recent Articles
1.
Huang J, Zhang Y, Qiu Y, Yao S, Qiu W, Peng J, et al.
Cell Rep
. 2024 Mar;
43(3):113905.
PMID: 38446660
Motivation-driven mating is a basic affair for the maintenance of species. However, the underlying molecular mechanisms that control mating motivation are not fully understood. Here, we report that NRG1-ErbB4 signaling...
2.
Ren D, Luo B, Chen P, Yu L, Xiong M, Fu Z, et al.
Cell Biosci
. 2023 Jul;
13(1):134.
PMID: 37480133
Background: Dendritic spines are the sites of excitatory synapses on pyramidal neurons, and their development is crucial for neural circuits and brain functions. The spine shape, size, or number alterations...
3.
Yao S, Xu M, Wang Y, Zhao S, Wang J, Chen G, et al.
Nat Commun
. 2023 Feb;
14(1):729.
PMID: 36759610
Alterations in energy metabolism are associated with depression. However, the role of glycolysis in the pathogenesis of depression and the underlying molecular mechanisms remain unexplored. Through an unbiased proteomic screen...
4.
Lin D, Li L, Chen W, Chen J, Ren D, Zheng Z, et al.
Mol Psychiatry
. 2023 Feb;
28(2):517.
PMID: 36755101
No abstract available.
5.
Lin D, Li L, Chen W, Chen J, Ren D, Zheng Z, et al.
Mol Psychiatry
. 2022 Dec;
28(2):908-918.
PMID: 36460727
Histidine phosphorylation (pHis), occurring on the histidine of substrate proteins, is a hidden phosphoproteome that is poorly characterized in mammals. LHPP (phospholysine phosphohistidine inorganic pyrophosphate phosphatase) is one of the...
6.
Pan H, Liu X, He Y, Zhou J, Liao C, You W, et al.
J Neurosci
. 2022 Jun;
42(29):5755-5770.
PMID: 35705488
Extinguishing the previously acquired fear is critical for the adaptation of an organism to the ever-changing environment, a process requiring the engagement of GABA receptors (GABARs). GABARs consist of tens...
7.
Hui T, Lai X, Dong X, Jing H, Liu Z, Fei E, et al.
Biology (Basel)
. 2021 Jun;
10(6).
PMID: 34063992
Low-density lipoprotein receptor-related protein 4 (Lrp4) is a critical protein involved in the Agrin-Lrp4-MuSK signaling pathway that drives the clustering of acetylcholine receptors (AChRs) at the neuromuscular junction (NMJ). Many...
8.
Sun D, Tan Z, Sun X, Liu Z, Chen W, Milibari L, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(16).
PMID: 33850017
Epilepsy, a common neurological disorder, is featured with recurrent seizures. Its underlying pathological mechanisms remain elusive. Here, we provide evidence for loss of neogenin (NEO1), a coreceptor for multiple ligands,...
9.
Sun D, Milibari L, Pan J, Ren X, Yao L, Zhao Y, et al.
Biol Psychiatry
. 2020 Nov;
89(6):600-614.
PMID: 33183762
Background: Dentate gyrus (DG), a "gate" that controls information flow into the hippocampus, plays important roles in regulating both cognitive (e.g., spatial learning and memory) and mood behaviors. Deficits in...
10.
Chen J, Zhou T, Guo A, Chen W, Lin D, Liu Z, et al.
Biology (Basel)
. 2020 Oct;
9(11).
PMID: 33114529
Metformin, a first-line drug for type 2 diabetes mellitus (T2DM), has been found to reduce depressive symptoms in patients with comorbid depression and other diseases. However, it is largely unclear...