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Weiyan Huang

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Articles 18
Citations 165
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Recent Articles
11.
Chien R, Mingqun L, Yan Q, Randolph N, Huang W, Wellman M, et al.
Microbiol Spectr . 2023 Oct; 11(6):e0263223. PMID: 37882777
The tick-borne obligatory intracellular bacterium infects humans as well as domesticated and wild animals, causing a febrile disease collectively called granulocytic anaplasmosis. The epidemiology and the host species specificity and...
12.
Huang W, Xia D, Bi W, Lai X, Yu B, Chen W
Stem Cell Res Ther . 2023 Oct; 14(1):293. PMID: 37817212
Peritoneal fibrosis (PF) is a pathophysiological condition caused by a variety of pathogenic factors. The most important features of PF are mesothelial-mesenchymal transition and accumulation of activated (myo-)fibroblasts, which hinder...
13.
Lin C, Huang W, Li X, Wang L, Yan F, Zhou X, et al.
J Clin Ultrasound . 2022 Dec; 51(3):465-471. PMID: 36464839
Objective: To investigate the diagnostic value of pelvic floor ultrasound parameters in combination for pelvic floor dysfunction (PFD), and to explore the risk factors. Methods: Forty PFD patients treated from...
14.
Huang W, Xiong Q, Lin M, Rikihisa Y
mBio . 2021 Sep; 12(5):e0229921. PMID: 34544283
The intracellular cholesterol transport protein Niemann-Pick type C1 (NPC1) and lipid-raft protein flotillin (FLOT) are required for cholesterol uptake by the obligatory intracellular bacterium Anaplasma phagocytophilum and for infection, and...
15.
Fu H, Cheng Y, Luo H, Rong Z, Li Y, Lu P, et al.
Neuroimmunomodulation . 2019 Apr; 26(2):67-76. PMID: 30928987
Objective(s): Neuroinflammation is an important contributor to the development of seizures and epilepsy. Micro-RNA-155 (miR-155) plays a critical role in immunity and -inflammation. This study aims to explore the function...
16.
Xiong Q, Lin M, Huang W, Rikihisa Y
mBio . 2019 Mar; 10(2). PMID: 30914515
is an obligatory intracellular bacterium that proliferates in membrane-bound inclusions. is dependent on cholesterol and acquire cholesterol from low-density lipoprotein (LDL) endocytosed by mammalian host cells. The mechanism of cholesterol...
17.
Yan Q, Lin M, Huang W, Teymournejad O, Johnson J, Hays F, et al.
Proc Natl Acad Sci U S A . 2018 Sep; 115(38):E8977-E8986. PMID: 30181274
, an obligatory intracellular bacterium, infects monocytes/macrophages by sequestering a regulator of endosomal traffic, the small GTPase RAB5, on its membrane-bound inclusions to avoid routing to host-cell phagolysosomes. How RAB5...
18.
Li Y, Li D, Zhao M, Huang S, Zhang Q, Lin H, et al.
Life Sci . 2018 Jul; 208:295-304. PMID: 30031062
Aims: Increasing evidence suggests that long noncoding RNAs act as critical regulators in various malignancies. Small nucleolar RNA host gene 6 (SNHG6) plays a role in the progression of human...
19.
Huang S, Li Y, Yuan X, Zhao M, Wang J, Li Y, et al.
Cell Death Differ . 2018 Jun; 26(3):516-530. PMID: 29899380
Ubiquilin4 (Ubqln4), a member of the UbL-UBA protein family, serves as an adaptor in the degradation of specific substrates via the proteasomal pathway. However, the biological function of Ubqln4 remains...
20.
Huang Y, Wang X, Huang W, Cheng Q, Zheng S, Guo S, et al.
Sci Rep . 2015 Aug; 5:12458. PMID: 26300278
Although small interfering RNAs (siRNAs) have been demonstrated to specifically silence their target genes in disease models and clinical trials, in vivo siRNA delivery is still the technical bottleneck that...