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Weichen Xu

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Articles 52
Citations 390
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Recent Articles
1.
Xu W, Fan Q, Meng Y, Nie Z, Sawut A, Xie S, et al.
Sci Rep . 2025 Mar; 15(1):8876. PMID: 40087334
Glaucoma is a leading cause of irreversible blindness worldwide, with its pathogenesis incompletely understood. Inflammation, as an important aspect of glaucoma, has attracted increasing attention. In this study, we performed...
2.
Gao B, Shi X, Zhao M, Ren F, Xu W, Gao N, et al.
ACS Omega . 2025 Mar; 10(8):7597-7608. PMID: 40060808
Microplastics are plastic particles with sizes of less than 5 mm. The ubiquity of microplastics in the environment has raised serious public health concerns. Microplastics could disturb the composition of...
3.
Han S, Luo Z, Bao S, Xiao Z, Xu W, Xie T, et al.
J Ethnopharmacol . 2025 Mar; 345:119577. PMID: 40058476
Ethnopharmacological Relevance: Platycodon grandiflorus root, is a widely used herb in East Asia for treating respiratory diseases, but research on its oral safety is limited. Aim Of The Study: This...
4.
Zhan R, Fang Y, Lou C, Chen N, Mo X, Jiao B, et al.
Adv Sci (Weinh) . 2025 Mar; :e2414397. PMID: 40047133
Postoperative cognitive dysfunction (POCD) frequently occurs after surgery, resulting in extended hospitalizations, higher healthcare expenses, and potential long-term cognitive impairment. Despite its significant impact, effective preventive and therapeutic strategies for...
5.
Li S, Yu J, Shen Y, Xiong B, Zhao D, Xu W, et al.
Nat Commun . 2025 Feb; 16(1):1499. PMID: 39929846
Obesity, a surging global health challenge, necessitates effective, accessible and innovative therapeutic models. Here we develop a spatiotemporally controllable microneedle (MN) drug delivery platform for sono-gene therapy to fight obesity....
6.
Sun G, Xu A, Yang X, Zhang L, Wang W, Sawut A, et al.
Retina . 2024 Dec; PMID: 39652822
Purpose: To investigate the distribution of macrophage-like cells (MLCs) across different stages of posterior vitreous detachment (PVD). Methods: A total of 168 eyes from 168 subjects were included. MLCs were...
7.
Hou X, Shen Y, Huang B, Li Q, Li S, Jiang T, et al.
J Nanobiotechnology . 2024 Oct; 22(1):667. PMID: 39472933
Preclinical studies demonstrating high cure rates with PD1/PD-L1 combinations have led to numerous clinical trials, but emerging results are disappointing. These combined immunotherapies are commonly employed for patients with refractory...
8.
Fang H, Wang W, Wang L, Zhu J, Lin W, Deng H, et al.
J Pharm Biomed Anal . 2024 Sep; 252:116475. PMID: 39326377
This study aimed to investigate how maternal asthma during pregnancy disrupts fetal lung development by altering lipid metabolism in the amniotic fluid, which is crucial for fetal development. A pregnancy-induced...
9.
Luo Z, Zhou W, Xie T, Xu W, Shi C, Xiao Z, et al.
Acta Pharm Sin B . 2024 Sep; 14(8):3385-3415. PMID: 39220868
Bile acids (BAs) are synthesized by the host liver from cholesterol and are delivered to the intestine, where they undergo further metabolism by gut microbes and circulate between the liver...
10.
Wang X, Xu W, Li J, Shi C, Guo Y, Shan J, et al.
Smart Med . 2024 Aug; 2(4):e20230039. PMID: 39188303
Nanotechnology, an emerging force, has infiltrated diverse domains like biomedical, materials, and environmental sciences. Nano-omics, an emerging fusion, combines nanotechnology with omics, boasting amplified sensitivity and resolution. This review introduces...