Wei Q Deng
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Explore the profile of Wei Q Deng including associated specialties, affiliations and a list of published articles.
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20
Citations
354
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Recent Articles
1.
Deng W, Belisario K, Munafo M, MacKillop J
Mol Psychiatry
. 2024 Aug;
30(2):608-618.
PMID: 39181994
Genomic correlates of impulsivity have been identified in several genome-wide association studies (GWAS) using cross-sectional designs, but no studies have investigated the molecular genetic correlates of impulsivity phenotypes using longitudinally...
2.
Deng W, Cawte N, Campbell N, Azab S, de Souza R, Lamri A, et al.
Elife
. 2024 Aug;
13.
PMID: 39141540
Background: Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood...
3.
Deng W, Pigeyre M, Azab S, Wilson S, Campbell N, Cawte N, et al.
Clin Epigenetics
. 2024 Jun;
16(1):74.
PMID: 38840168
Background: Epigenetic modifications, particularly DNA methylation (DNAm) in cord blood, are an important biological marker of how external exposures during gestation can influence the in-utero environment and subsequent offspring development....
4.
Pathan N, Deng W, Di Scipio M, Khan M, Mao S, Morton R, et al.
Nat Commun
. 2024 Feb;
15(1):1245.
PMID: 38336875
It has been postulated that rare coding variants (RVs; MAF < 0.01) contribute to the "missing" heritability of complex traits. We developed a framework, the Rare variant heritability (RARity) estimator,...
5.
Deng W, Belisario K, Gray J, Levitt E, MacKillop J
Alcohol Alcohol
. 2024 Jan;
59(2).
PMID: 38261344
Aims: This study uses a high-resolution phenome-wide approach to evaluate the motivational mechanisms of polygenic risk scores (PRSs) that have been robustly associated with coarse alcohol phenotypes in large-scale studies....
6.
Deng W, Belisario K, Gray J, Levitt E, Mohammadi-Shemirani P, Singh D, et al.
Genes Brain Behav
. 2023 Apr;
22(3):e12848.
PMID: 37060189
Impulsivity refers to a number of conceptually related phenotypes reflecting self-regulatory capacity that are considered promising endophenotypes for mental and physical health. Measures of impulsivity can be broadly grouped into...
7.
Deng W, Sun L
G3 (Bethesda)
. 2022 Feb;
12(4).
PMID: 35201341
A joint analysis of location and scale can be a powerful tool in genome-wide association studies to uncover previously overlooked markers that influence a quantitative trait through both mean and...
8.
Author Correction: A machine-learning heuristic to improve gene score prediction of polygenic traits
Pare G, Mao S, Deng W
Sci Rep
. 2019 Nov;
9(1):17507.
PMID: 31745232
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Deng W, Mao S, Kalnapenkis A, Esko T, Magi R, Pare G, et al.
Genet Epidemiol
. 2019 Jul;
43(7):815-830.
PMID: 31332826
Genotype-stratified variance of a quantitative trait could differ in the presence of gene-gene or gene-environment interactions. Genetic markers associated with phenotypic variance are thus considered promising candidates for follow-up interaction...
10.
Pare G, Mao S, Deng W
Genet Epidemiol
. 2018 Aug;
42(7):636-647.
PMID: 30156736
Complex traits can share a substantial proportion of their polygenic heritability. However, genome-wide polygenic correlations between pairs of traits can mask heterogeneity in their shared polygenic effects across loci. We...