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Wei-Zhong Wang

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Recent Articles
11.
Fan J, Xiao Y, Feng Y, Niu L, Tan X, Sun J, et al.
Front Cardiovasc Med . 2023 Apr; 10:1084611. PMID: 37051068
Background: Cold exposure has been considered an essential risk factor for the global disease burden, while its role in cardiovascular diseases is still underappreciated. The increase in frequency and duration...
12.
Wang W, Zhu L, Leng Y, Wang Y, Shi T, Wang W, et al.
Nutrients . 2023 Feb; 15(3). PMID: 36771313
Gut microbiota is the largest and most complex microflora in the human body, which plays a crucial role in human health and disease. Over the past 20 years, the bidirectional...
13.
Ye P, Duan W, Leng Y, Wang Y, Tan X, Wang W
Front Cardiovasc Med . 2022 Oct; 9:974035. PMID: 36312232
Cardiovascular disease is the leading cause of death globally among non-communicable diseases, which imposes a serious socioeconomic burden on patients and the healthcare system. Therefore, finding new strategies for preventing...
14.
Duan W, Ye P, Leng Y, Liu D, Sun J, Tan X, et al.
Neurosci Lett . 2022 Oct; 791:136917. PMID: 36252850
Circadian rhythm plays a significant role in maintaining the function of the cardiovascular system. Emerging studies have demonstrated that circadian disruption enhances the risk of cardiovascular diseases by activating the...
15.
Tan X, Ye P, Li W, Gao Y, Leng Y, Duan W, et al.
Am J Physiol Regul Integr Comp Physiol . 2022 Oct; 323(6):R861-R874. PMID: 36222883
Hypertension is characterized by sympathetic hyperactivity, which is related to the overexcitation of the presympathetic neurons in the rostral ventrolateral medulla (RVLM). Nitric oxide (NO) has been reported to be...
16.
Fan J, Wang W, Tan X, Ye P, Li J, Niu L, et al.
J Hypertens . 2022 Oct; 40(12):2394-2405. PMID: 36189462
Objective: Cyclooxygenase (COX) is critical in regulating cardiovascular function, but its role involved in the central control of blood pressure (BP) is uncovered. The tonic glutamatergic inputs to the rostral...
17.
Ren C, Wu Z, Wang W, Tan X, Yang Y, Wang Y, et al.
Free Radic Biol Med . 2022 Jun; 188:1-13. PMID: 35688305
The rostral ventrolateral medulla (RVLM) is a pivotal region in the central regulation of blood pressure (BP). It has been documented that silent information regulator 2 homolog 1 (SIRT1), a...
18.
Xiao Y, Wang W, Gao Y, Li W, Tan X, Wang Y, et al.
J Cardiovasc Transl Res . 2022 May; 15(3):500-513. PMID: 35501543
Sympathetic hyperactivity plays an important role in the progression of chronic heart failure (CHF). It is reported that inflammation in the rostral ventrolateral medulla (RVLM), a key region for sympathetic...
19.
Sun J, Tan X, Ge L, Xu M, Wang W
Front Physiol . 2021 Jul; 12:694135. PMID: 34220554
β-Arrestin1 is a multifunctional scaffold protein with the ability to interact with diverse signaling molecules independent of G protein-coupled receptors. We previously reported that overexpression of β-arrestin1 in the rostral...
20.
Tan X, Jiao P, Sun J, Wang W, Ye P, Wang Y, et al.
Front Neurosci . 2021 Apr; 15:657825. PMID: 33897365
Oxidative stress in the rostral ventrolateral medulla (RVLM), a key region for blood pressure (BP) regulation, has been demonstrated to be responsible for the overactivity of the sympathetic nervous system...