Wayne L Gerlach
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Explore the profile of Wayne L Gerlach including associated specialties, affiliations and a list of published articles.
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4
Citations
120
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Recent Articles
1.
Allen R, Miller J, Chitty J, Fist A, Gerlach W, Larkin P
Plant Biotechnol J
. 2007 Sep;
6(1):22-30.
PMID: 17854406
We demonstrate that both over-expression and suppression of the gene encoding the morphinan pathway enzyme salutaridinol 7-O-acetyltransferase (SalAT) in opium poppy affects the alkaloid products that accumulate. Over-expression of the...
2.
Larkin P, Miller J, Allen R, Chitty J, Gerlach W, Frick S, et al.
Plant Biotechnol J
. 2007 Jan;
5(1):26-37.
PMID: 17207254
Only plants of the Papaver genus (poppies) are able to synthesize morphinan alkaloids, and cultivation of P. somniferum, opium poppy, remains critical for the production and supply of morphine, codeine...
3.
Allen R, Millgate A, Chitty J, Thisleton J, Miller J, Fist A, et al.
Nat Biotechnol
. 2004 Nov;
22(12):1559-66.
PMID: 15543134
We report on the silencing of codeinone reductase (COR) in the opium poppy, Papaver somniferum, using a chimeric hairpin RNA construct designed to silence all members of the multigene COR...
4.
Millgate A, Pogson B, Wilson I, Kutchan T, Zenk M, Gerlach W, et al.
Nature
. 2004 Sep;
431(7007):413-4.
PMID: 15386001
The opium poppy is a source of the pharmaceuticals codeine, morphine and their derived analgesics. Here we describe the initial characterization of the poppy mutant known as top1 (for 'thebaine...