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Wayne Conlan

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Articles 16
Citations 633
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Recent Articles
1.
Kiattiburut W, Zhi R, Lee S, Foo A, Hickling D, Keillor J, et al.
Hum Reprod . 2018 Oct; 33(12):2175-2183. PMID: 30357408
Study Question: Do the truncated LL-37 peptides, GI-20 and GF-17, have spermicidal activity and microbicidal effects on the sexually transmitted infection (STI) pathogen Neisseria gonorrhoeae with equivalent potency to LL-37?...
2.
Alimonti J, Ribecco-Lutkiewicz M, Sodja C, Jezierski A, Stanimirovic D, Liu Q, et al.
Fluids Barriers CNS . 2018 May; 15(1):15. PMID: 29759080
Zika virus (ZIKV) is a flavivirus that is highly neurotropic causing congenital abnormalities and neurological damage to the central nervous systems (CNS). In this study, we used a human induced...
3.
Golovliov I, Lindgren H, Eneslatt K, Conlan W, Mosnier A, Henry T, et al.
Front Cell Infect Microbiol . 2016 Dec; 6:152. PMID: 27933275
is a highly virulent intracellular bacterium and cell-mediated immunity is critical for protection, but mechanisms of protection against highly virulent variants, such as the prototypic strain strain SCHU S4, are...
4.
Rigard M, Broms J, Mosnier A, Hologne M, Martin A, Lindgren L, et al.
PLoS Pathog . 2016 Sep; 12(9):e1005821. PMID: 27602570
The virulence of Francisella tularensis, the etiological agent of tularemia, relies on an atypical type VI secretion system (T6SS) encoded by a genomic island termed the Francisella Pathogenicity Island (FPI)....
5.
Binesse J, Lindgren H, Lindgren L, Conlan W, Sjostedt A
Infect Immun . 2015 Mar; 83(6):2255-63. PMID: 25802058
Francisella tularensis is a facultative intracellular bacterium utilizing macrophages as its primary intracellular habitat and is therefore highly capable of resisting the effects of reactive oxygen species (ROS), potent mediators...
6.
Lindgren M, Tancred L, Golovliov I, Conlan W, Twine S, Sjostedt A
Infect Immun . 2014 Jun; 82(9):3622-35. PMID: 24935978
Previously, we identified a spontaneous, essentially avirulent mutant, FSC043, of the highly virulent strain SCHU S4 of Francisella tularensis subsp. tularensis. We have now characterized the phenotype of the mutant...
7.
Golovliov I, Twine S, Shen H, Sjostedt A, Conlan W
PLoS One . 2013 Nov; 8(11):e78671. PMID: 24236032
Francisella tularensis subsp. tularensis is a highly virulent pathogen for humans especially if inhaled. Consequently, it is considered to be a potential biothreat agent. An experimental vaccine, F. tularensis live...
8.
Ryden P, Twine S, Shen H, Harris G, Chen W, Sjostedt A, et al.
Mol Immunol . 2012 Dec; 54(1):58-67. PMID: 23201853
Francisella tularensis subspecies tularensis is an extremely virulent facultative intracellular bacterial pathogen capable of causing significant mortality in humans when inhaled. Consequently, subspecies tularensis was developed as a biological weapon...
9.
Twine S, Shen H, Harris G, Chen W, Sjostedt A, Ryden P, et al.
Vaccine . 2012 Apr; 30(24):3634-45. PMID: 22484348
Francisella tularensis subspecies tularensis is highly virulent for humans especially when it is inhaled. Therefore, it has the potential to be used as a biothreat agent. Vaccines against F. tularensis...
10.
Shen H, Harris G, Chen W, Sjostedt A, Ryden P, Conlan W
PLoS One . 2010 Oct; 5(10):e13349. PMID: 20967278
Background: Francisella tularensis is a facultative intracellular bacterial pathogen and the etiological agent of tularemia. The subspecies F. tularensis tularensis is especially virulent for humans when inhaled and respiratory tularemia...