Wayne C Drevets
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Explore the profile of Wayne C Drevets including associated specialties, affiliations and a list of published articles.
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266
Citations
17254
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Recent Articles
1.
Kosik-Gonzalez C, Fu D, Chen L, Lane R, Bloch M, DelBello M, et al.
J Am Acad Child Adolesc Psychiatry
. 2025 Mar;
PMID: 40058488
Objective: To evaluate the efficacy, safety, and tolerability of esketamine nasal spray versus psychoactive placebo (oral midazolam) in rapidly reducing depressive symptoms in adolescents with major depressive disorder at imminent...
2.
Miller A, Berk M, Bloch G, Briquet-Laugier V, Brouillon C, Cuthbert B, et al.
Brain Behav Immun
. 2025 Jan;
125:319-329.
PMID: 39828008
Despite tremendous advancements in neuroscience, there has been limited impact on patient care. Current psychiatric treatments are largely non-specific, and drug development is hindered by outdated, overinclusive diagnostic categories and...
3.
Mesens S, Kezic I, Van Der Ark P, Etropolski M, Pandina G, Benes H, et al.
Mol Psychiatry
. 2024 Dec;
PMID: 39663378
The antidepressant efficacy and safety of seltorexant monotherapy in major depressive disorder (MDD) was investigated in a placebo-controlled, placebo lead-in, randomized, double-blind, phase 1b study. Participants were randomized to receive...
4.
Morrison R, Singh J, Daly E, Fedgchin M, Ochs-Ross R, Karcher K, et al.
Int J Neuropsychopharmacol
. 2024 Nov;
27(11).
PMID: 39514643
Background: While esketamine is effective in treatment-resistant depression (TRD), detailed information about the effect of esketamine on cognition is relatively scarce. This analysis assessed the effect of short-term (3 double-blind...
5.
Klein M, Bangerter A, Halter R, Cooper K, Aguilar Z, Canuso C, et al.
Neuropsychopharmacology
. 2024 Oct;
50(2):480-487.
PMID: 39414987
JNJ-42165279, a highly selective and orally bioavailable fatty acid amide (FAA) hydrolase inhibitor, was evaluated for efficacy and safety in adolescents and adults with autism spectrum disorder (ASD) in this...
6.
Arshadi M, Elmaadawi A, Nasr S, Jayathilake K, Rassnick S, Ford L, et al.
J Clin Psychopharmacol
. 2024 Sep;
44(5):481-491.
PMID: 39250138
Background: The serotonin type 7 (5-HT7) receptor is one of 14 5-HT receptors. It has received attention for its possible role in mood disorders and cognition. The 5-HT7 receptor antagonist,...
7.
Schmidt M, Kezic I, Popova V, Melkote R, Van Der Ark P, Pemberton D, et al.
Neuropsychopharmacology
. 2024 Apr;
49(9):1437-1447.
PMID: 38649428
This was a double-blind, randomized, phase 2 study of adults (18-64 years) with DSM-5 diagnosis of major depressive disorder (MDD), with moderate-to-severe episode severity (Montgomery-Åsberg Depression Rating Scale [MADRS] ≥25)...
8.
Lombardo G, Mondelli V, Worrell C, Sforzini L, Mariani N, Nikkheslat N, et al.
J Affect Disord
. 2024 Mar;
356:167-176.
PMID: 38494137
Sex hormones have biological effects on inflammation, and these might contribute to the sex-specific features of depression. C-reactive protein (CRP) is the most widely used inflammatory biomarker and consistent evidence...
9.
Wang L, Chen X, Gu X, De Smedt H, Popova V, Fu D, et al.
Neuropsychiatr Dis Treat
. 2024 Jan;
19:2857-2870.
PMID: 38161513
Purpose: This meta-analysis assessed whether atypical antipsychotics (AAPs) and esketamine nasal spray (ESK-NS), which are mechanistically distinct, differ in antidepressant outcomes. Patients And Methods: Data were extracted from 12 trials...
10.
Vairavan S, Rashidisabet H, Li Q, Ness S, Morrison R, Soares C, et al.
Sci Rep
. 2023 Oct;
13(1):18596.
PMID: 37903878
Major depressive disorder (MDD) is a chronic illness wherein relapses contribute to significant patient morbidity and mortality. Near-term prediction of relapses in MDD patients has the potential to improve outcomes...