Wayne B Severn
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Explore the profile of Wayne B Severn including associated specialties, affiliations and a list of published articles.
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4
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44
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Recent Articles
1.
Denis M, Ainge G, Larsen D, Severn W, Painter G
Immunopharmacol Immunotoxicol
. 2009 Oct;
31(4):577-82.
PMID: 19874225
We recently described the synthesis of an ether linked analogue of phosphatidylinositol dimannoside (PIM(2)ME). In the current study, PIM(2)ME was found to significantly enhance the release of the key Th1...
2.
Parlane N, Denis M, Severn W, Skinner M, Painter G, La Flamme A, et al.
Immunol Invest
. 2008 Feb;
37(2):129-42.
PMID: 18300038
The development of defined sub-unit vaccines requires the inclusion in the vaccine of an immunological adjuvant. The most important property of adjuvants for vaccines aimed at inducing optimal protection against...
3.
Zajonc D, Ainge G, Painter G, Severn W, Wilson I
J Immunol
. 2006 Sep;
177(7):4577-83.
PMID: 16982895
Mycobacterial phosphatidylinositol tetramannosides (PIM4) are agonists for a distinct population of invariant human (Valpha24) and mouse (Valpha14) NKT cells, when presented by CD1d. We determined the crystal structure at 2.6-A...
4.
Furneaux R, Landersjo C, McCullough J, Severn W
Carbohydr Res
. 2005 May;
340(9):1618-24.
PMID: 15907815
The deacylated phosphatidylinositol manno-oligosaccharides (dPIMs) from the glycosyl phosphatidylinositol (GPI) carbohydrate antigen anchor of Gordonia sputi were the known 2,6-di-O-alpha-mannopyranosyl-myo-inositol glycerophosphate (dPIM-2) and the illustrated novel compound (dPIM-8), which could...