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Wayne A Aldrich

Explore the profile of Wayne A Aldrich including associated specialties, affiliations and a list of published articles. Areas
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Citations 98
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Recent Articles
1.
Guo B, Liu Z, Aldrich W, Lopez R
Breast Cancer Res Treat . 2005 Sep; 93(2):169-75. PMID: 16187237
We previously identified a CD2-initiated signaling pathway which inhibits activation-induced cell death in mitogen-stimulated human gammadelta-T cells permitting the large-scale expansion of these cells. Here we report the innate anti-tumor...
2.
Korokhov N, de Gruijl T, Aldrich W, Triozzi P, Banerjee P, Gillies S, et al.
Cancer Biol Ther . 2005 Mar; 4(3):289-94. PMID: 15753654
Dendritic cells (DCs) are a central element in the development of antigen-specific immune responses. The lack of a specific and efficient technique for the in vivo delivery of antigens to...
3.
Ponnazhagan S, Mahendra G, Lima J, Aldrich W, Jenkins C, Ren C, et al.
Hum Gene Ther . 2004 Sep; 15(9):856-64. PMID: 15353040
Recombinant adeno-associated virus 2 (rAAV) vectors have been successfully used for sustained expression of therapeutic genes. The potential of using rAAV as a cancer vaccine vector and the impact of...
4.
Korokhov N, Mikheeva G, Krendelshchikov A, Belousova N, Simonenko V, Krendelshchikova V, et al.
J Virol . 2003 Dec; 77(24):12931-40. PMID: 14645549
A potential barrier to the development of genetically targeted adenovirus (Ad) vectors for cell-specific delivery of gene therapeutics lies in the fact that several types of targeting protein ligands require...
5.
Belousova N, Korokhov N, Krendelshchikova V, Simonenko V, Mikheeva G, Triozzi P, et al.
J Virol . 2003 Oct; 77(21):11367-77. PMID: 14557622
The success of gene therapy depends on the specificity of transgene delivery by therapeutic vectors. The present study describes the use of an adenovirus (Ad) fiber replacement strategy for genetic...