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Wararat Kittikulsuth

Explore the profile of Wararat Kittikulsuth including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 313
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Recent Articles
1.
Sakamoto K, Kittikulsuth W, Miyako E, Steeve A, Ishimura R, Nakagawa S, et al.
PLoS One . 2023 Jul; 18(7):e0286651. PMID: 37405999
We have previously demonstrated that KS-133 is a specific and potent antagonist of vasoactive intestinal peptide receptor 2 (VIPR2). We have also shown that vasoactive intestinal peptide-VIPR2 signaling affects the...
2.
Kittikulsuth W, Nakano D, Kitada K, Uyama T, Ueda N, Asano E, et al.
Sci Rep . 2023 Jan; 13(1):927. PMID: 36650220
Macrophages are a major population of immune cells in solid cancers, especially colorectal cancers. Tumor-associated macrophages (TAMs) are commonly divided into M1-like (tumor suppression) and M2-like (tumor promotion) phenotypes. Vasoactive...
3.
Kidoguchi S, Kitada K, Nakajima K, Nakano D, Ohsaki H, Kittikulsuth W, et al.
Life Sci . 2021 Dec; 289:120192. PMID: 34871664
Aims: The number of cancer survivors with cardiovascular disease is increasing. However, the effect of cancer on body fluid regulation remains to be clarified. In this study, we evaluated body...
4.
Zhang A, Nakano D, Kittikulsuth W, Yamashita Y, Nishiyama A
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34360935
Proximal tubules (PTs) take up most of the glucose in the glomerular filtrate and return it to peritubular capillary blood. Sodium-glucose cotransporter 2 (SGLT2) at the apical membrane takes up...
5.
Kittikulsuth W, Nakano D, Kitada K, Suzuki N, Yamamoto M, Nishiyama A
Am J Physiol Renal Physiol . 2021 Jun; 321(2):F170-F178. PMID: 34180718
Pericytes play an important role in the recovery process after ischemic injury of many tissues. Brain pericytes in the peri-infarct area express macrophage markers in response to injury stimuli and...
6.
Zhang A, Nakano D, Morisawa N, Kitada K, Kittikulsuth W, Rahman A, et al.
J Pharmacol Sci . 2021 May; 146(2):98-104. PMID: 33941326
Hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitors were developed for treatment of renal anemia. Patients applicable for HIF-PHD inhibitor treatment experience complications such as chronic kidney disease, whereby water and electrolyte...
7.
Li L, Nakano D, Zhang A, Kittikulsuth W, Morisawa N, Ohsaki H, et al.
J Pharmacol Sci . 2020 Oct; 144(4):229-236. PMID: 33070842
The kidneys are the major organs for erythropoietin (EPO) production in adults, and thus, kidney damage results in reduced EPO levels and anemia. Inhibitors of Hypoxia-inducible factor-prolyl hydroxylase domain-containing protein...
8.
Yamazaki D, Konishi Y, Morikawa T, Kobara H, Masaki T, Hitomi H, et al.
J Diabetes Investig . 2019 Dec; 11(4):834-843. PMID: 31880858
Aims/introduction: Clinical studies have shown that treatment with inhibitors of sodium-glucose cotransporter 2 (SGLT2) significantly increases the hematocrit in patients with type 2 diabetes. To investigate whether SGLT2 inhibitors directly...
9.
Kittikulsuth W, Friedman P, van Hoek A, Gao Y, Kohan D
BMC Nephrol . 2017 Sep; 18(1):292. PMID: 28882112
Background: The distal convoluted tubule (DCT) is an important nephron site for parathyroid hormone (PTH) and calcitonin regulation of urinary divalent cation excretion. These hormones exert their effects on the...
10.
Hasan A, Kittikulsuth W, Yamaguchi F, Ansary T, Rahman A, Shibayama Y, et al.
Exp Cell Res . 2017 Jul; 358(2):343-351. PMID: 28689812
Hypoxia predisposes renal fibrosis. This study was conducted to identify novel approaches to ameliorate the pathogenic effect of hypoxia. Using human proximal tubular epithelial cells we showed that a pan-phosphodiesterase...