Wanrong Man
Overview
Explore the profile of Wanrong Man including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
433
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Recent Articles
1.
Zhang Y, Zhu Z, Cao Y, Xiong Z, Duan Y, Lin J, et al.
Clin Transl Med
. 2023 Sep;
13(9):e1406.
PMID: 37743632
Background: As the main pathological basis for various cardiovascular and cerebrovascular diseases, atherosclerosis has become one of the leading causes of death and disability worldwide. Emerging evidence has suggested that...
2.
Zhang X, Duan Y, Zhang X, Jiang M, Man W, Zhang Y, et al.
BMC Med
. 2023 May;
21(1):197.
PMID: 37237266
Background: Microvascular complications are associated with an overtly increased risk of adverse outcomes in patients with diabetes including coronary microvascular injury which manifested as disruption of adherens junctions between cardiac...
3.
Zhang Y, Cao Y, Zheng R, Xiong Z, Zhu Z, Gao F, et al.
Theranostics
. 2022 Nov;
12(17):7250-7266.
PMID: 36438502
Extracellular matrix (ECM) remodeling, a key pathological feature in diabetic cardiomyopathy (DCM), is triggered by oxidative stress, inflammation, and various metabolic disorders in the heart. Cardiac fibroblasts (CFs) are the...
4.
Man W, Song X, Xiong Z, Gu J, Lin J, Gu X, et al.
Front Cardiovasc Med
. 2022 Sep;
9:1003282.
PMID: 36172581
As a vital adipokine, Adipsin is closely associated with cardiovascular risks. Nevertheless, its role in the onset and development of cardiovascular diseases remains elusive. This study was designed to examine...
5.
Duan Y, Zhang X, Zhang X, Lin J, Shu X, Man W, et al.
Biochim Biophys Acta Mol Basis Dis
. 2022 Sep;
1868(12):166533.
PMID: 36064133
Phagocytosis of oxidized low-density lipoprotein (OxLDL) by macrophages yields "foam cells" and serves as a hallmark of atherosclerotic lesion. Adipsin is a critical component of the complement activation pathway. Recent...
6.
Sun D, Wang H, Su Y, Lin J, Zhang M, Man W, et al.
Iran J Basic Med Sci
. 2021 May;
24(2):150-159.
PMID: 33953853
Objectives: Physical exercise has emerged as an effective therapy to mitigate cardiac remodelling in diabetic cardiomyopathy (DCM). The results of our previous studies revealed mammalian sterile 20-like kinase 1 (Mst1)...
7.
Feng X, Wang S, Yang X, Lin J, Man W, Dong Y, et al.
Front Cell Dev Biol
. 2021 Feb;
8:628842.
PMID: 33553168
The disruption of mitochondrial dynamics is responsible for the development of diabetic cardiomyopathy (DCM). However, the mechanisms that regulate the balance of mitochondrial fission and fusion are not well-understood. Wild-type,...
8.
Zhang Y, Dong Y, Xiong Z, Zhu Z, Gao F, Wang T, et al.
Diabetes Metab Syndr Obes
. 2020 Dec;
13:4801-4808.
PMID: 33324079
Background: Endothelial-to-mesenchymal transition (EndMT) is an important source of myofibroblasts that directly affects cardiac function in diabetic cardiomyopathy (DCM) via an unknown underlying mechanism. Sirt6 is a member of the...
9.
Man W, Gu J, Wang B, Zhang M, Hu J, Lin J, et al.
Front Physiol
. 2020 Sep;
11:1082.
PMID: 32982797
Cardiac remodeling and dysfunction are responsible for the high mortality after myocardial infarction (MI). We assessed the potential for Shank3 to alleviate the post-infarction cardiac dysfunction. The experimental MI mice...
10.
Xiong Z, Li Y, Zhao Z, Zhang Y, Man W, Lin J, et al.
Biochim Biophys Acta Mol Basis Dis
. 2020 Apr;
1866(8):165806.
PMID: 32320827
Diabetic cardiomyopathy (DCM) accounts for increasing deaths of diabetic patients, and effective therapeutic targets are urgently needed. Myocardial lipotoxicity, which is caused by cardiac non-oxidative metabolic fatty acids and cardiotoxic...