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Wang-Sheng Wang

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Articles 30
Citations 186
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Recent Articles
1.
Li M, Sun K, Wang W
Sheng Li Xue Bao . 2025 Mar; 77(1):151-166. PMID: 40065623
A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) represent a diverse family of secreted metalloproteinases, comprising 19 distinct members categorized into five groups based on their substrate specificity: proteoglycanases, procollagen...
2.
Wang D, Zhang M, Wang W, Chu W, Zhai J, Sun Y, et al.
Front Med . 2024 Dec; 19(1):149-169. PMID: 39648233
Polycystic ovary syndrome (PCOS) is the predominant cause of subfertility in reproductive-aged women; however, its pathophysiology remains unknown. Neurotensin (NTS) is a member of the gut-brain peptide family and is...
3.
Lei W, Zhang F, Li M, Pan F, Ling L, Lu J, et al.
BMC Med . 2024 Oct; 22(1):432. PMID: 39379940
Background: Parturition is an inflammation process. Exaggerated inflammatory reactions in infection lead to preterm birth. Although nuclear factor kappa B (NF-κB) has been recognized as a classical transcription factor mediating...
4.
Ling L, Zhou Q, Zhang F, Lei W, Li M, Lu J, et al.
Front Immunol . 2024 Sep; 15:1459489. PMID: 39290694
Introduction: Fetal membrane inflammation is an integral event of parturition. However, excessive pro-inflammatory cytokines can impose threats to the fetus. Coincidentally, the fetal membranes express abundant 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1),...
5.
Pan F, Zhang F, Li M, Liang Y, Wang W, Sun K
Antioxid Redox Signal . 2024 Jun; 42(1-3):16-35. PMID: 38877798
Azithromycin (AZM) is widely used to treat mycoplasma infection in pregnancy. However, there is no adequate evaluation of its side effect on the placenta. In this study, using human placental...
6.
Li M, Lu J, Zhang F, Lei W, Pan F, Lin Y, et al.
Commun Biol . 2024 Mar; 7(1):301. PMID: 38461223
Hyalectan cleavage may play an important role in extracellular matrix remodeling. However, the proteolytic enzyme responsible for hyalectan degradation for fetal membrane rupture at parturition remains unknown. Here, we reveal...
7.
Zhang C, Wang W, Yao G, Zhu Y, Lin Y, Lu J, et al.
Hum Reprod Open . 2024 Feb; 2024(1):hoae002. PMID: 38333108
Study Question: Does palmitic acid (PA), the most common saturated free fatty acid (FFA) in individuals with obesity, contribute to anovulation through upregulation of the collagen-crosslinking enzyme lysyl oxidase (LOX)...
8.
Zhu Y, Pan F, Gan X, Liu Y, Wang W, Sun K
Endocrinology . 2023 Dec; 165(2). PMID: 38146648
Progesterone synthesized in the placenta is essential for pregnancy maintenance. CYP11A1 is a key enzyme in progesterone synthesis, and its expression increases greatly during trophoblast syncytialization. However, the underlying mechanism...
9.
Zhang F, Lu J, Lei W, Li M, Pan F, Lin Y, et al.
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37446059
Inflammation of the fetal membranes is an indispensable event of parturition, with increasing prostaglandin E2 (PGE2) synthesis as one of the ultimate products that prime labor onset. In addition to...
10.
Lei W, Zhang F, Lin Y, Li M, Pan F, Sun K, et al.
Mol Med . 2023 Jul; 29(1):88. PMID: 37403020
Background: Inflammation of the fetal membranes is an indispensable event of labor onset at both term and preterm birth. Interleukin-33 (IL-33) is known to participate in inflammation via ST2 (suppression...