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Wanchang Cui

Explore the profile of Wanchang Cui including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 341
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Recent Articles
11.
Cui W, Zhang P, Hankey K, Xiao M, Farese A, MacVittie T
Health Phys . 2021 Sep; 121(4):331-344. PMID: 34546215
To study the molecular and cellular mechanisms of radiation-induced lung injury (RILI) in a non-human primate model, Rhesus macaques were irradiated with lethal doses of radiation to the whole thorax....
12.
Farese A, Booth C, Tudor G, Cui W, Cohen E, Parker G, et al.
Health Phys . 2021 Sep; 121(4):282-303. PMID: 34546213
The dose response relationship and corresponding values for mid-lethal dose and slope are used to define the dose- and time-dependent parameters of the hematopoietic acute radiation syndrome. The characteristic time...
13.
Wang L, Zhai M, Lin B, Cui W, Hull L, Li X, et al.
Radiat Res . 2021 Apr; 196(1):113-127. PMID: 33914884
Radiation combined injury (RCI, radiation exposure coupled with other forms of injury, such as burn, wound, hemorrhage, blast, trauma and/or sepsis) comprises approximately 65% of injuries from a nuclear explosion,...
14.
Li X, Cui W, Hull L, Wang L, Yu T, Xiao M
Sci Rep . 2020 Oct; 10(1):18674. PMID: 33122671
Recent studies suggested that radiation exposure causes local and systemic inflammatory responses and induces cell and tissue damage. We have reported that IL-18 plays an important role in radiation-induced injury....
15.
Kiang J, Smith J, Cannon G, Anderson M, Ho C, Zhai M, et al.
Cell Biosci . 2020 May; 10:63. PMID: 32426105
Background: Compared to radiation injury alone (RI), radiation injury combined wound (CI) further enhances acute radiation syndrome and subsequently mortality. We previously reported that therapy with Ghrelin, the 28-amino-acid-peptide secreted...
16.
Cui W, Hankey K, Zhang P, Bolduc D, Bunger R, Xiao M, et al.
Radiat Res . 2020 May; 194(1):81-88. PMID: 32352866
Inflammatory cytokines have been suggested to play important roles in radiation-induced lung injury (RILI). Identifying significantly changed circulating and tissue cytokines after thoracic irradiation will aid in deciphering the mechanism...
17.
Cui W, Li X, Hull L, Xiao M
Sci Rep . 2019 Apr; 9(1):6385. PMID: 31015536
Cryptococcus neoformans is a basidiomycete fungus that is highly resistant to ionizing radiation and has been identified in highly radioactive environments. Transcription factors (TFs) are master regulators of gene expression...
18.
Cui W, Li X, Hull L, Xiao M
PLoS One . 2018 Nov; 13(11):e0207071. PMID: 30408089
DNA damage has been considered to be the universal critical lesion in cells after exposure to ionizing radiation. Measuring radiation-induced DNA damage is important to understand the mechanisms of radiation-induced...
19.
Li X, Cui W, Hull L, Smith J, Kiang J, Xiao M
Radiat Res . 2018 Oct; 190(6):612-622. PMID: 30311842
In this study, we investigated the effects of low-to-moderate doses of radiation in mice, given our limited understanding of the health risks associated with these exposures. Here, we demonstrate the...
20.
Chen Z, Fang Y, Zhang S, Li L, Wang L, Zhang A, et al.
Int J Radiat Oncol Biol Phys . 2018 Sep; 103(1):208-216. PMID: 30171878
Purpose: Radiation-induced pulmonary fibrosis (RIPF) is a severe and life-threatening complication of radiation therapy in patients with thoracic cancer; however, the exact molecular mechanisms remain unknown, and there is no...