Walaa Darwiche
Overview
Explore the profile of Walaa Darwiche including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
113
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Recent Articles
1.
Ballout N, Toumieux S, Darwiche W, Gomila C, Trecherel E, Accadbled F, et al.
Pharmaceuticals (Basel)
. 2025 Feb;
18(2).
PMID: 40006029
: Delays in bone healing and complications of remodeling constitute a major medical problem-particularly in older adults and patients with comorbidities. Current therapeutic approaches are based on strategies that promote...
2.
Giovannangeli L, Magry V, Jobic F, Messaoudi K, Darwiche W, Perriere M, et al.
Am J Med Genet A
. 2024 Dec;
:e63968.
PMID: 39704251
Proteus syndrome (PS) is a rare disorder (< 1/1000000), marked by progressive overgrowth commonly impacting the skeleton, skin, adipose tissue, and central nervous system. Clinical criteria were established in 2019....
3.
Ballout N, Boullier A, Darwiche W, Ait-Mohand K, Trecherel E, Gallego T, et al.
Pharmaceuticals (Basel)
. 2023 Nov;
16(11).
PMID: 38004380
Bone fracture healing is a complex biological process involving four phases coordinated over time: hematoma formation, granulation tissue formation, bony callus formation, and bone remodelling. Bone fractures represent a significant...
4.
Saldarriaga M, Darwiche W, Jayabalan D, Monge J, Rosenbaum C, Pearse R, et al.
Front Oncol
. 2022 Nov;
12:1020011.
PMID: 36387095
Recent insight in the genomic landscape of newly diagnosed multiple myeloma (NDMM) and its precursor conditions, monoclonal gammopathy of uncertain significance (MGUS), and smoldering myeloma have allowed the identification of...
5.
Mansour A, Darwiche W, Yaker L, Da Nascimento S, Gomila C, Rossi C, et al.
Front Cell Dev Biol
. 2020 Dec;
8:589761.
PMID: 33330469
Objective: Vascular calcification (VC) is an active process during which vascular smooth muscle cells (VSMCs) undergo an osteogenic switch and release extracellular vesicles (EVs). In turn, the EVs serve as...
6.
Darwiche W, Gomila C, Ouled-Haddou H, Naudot M, Doualle C, Morel P, et al.
J Exp Clin Cancer Res
. 2020 Oct;
39(1):228.
PMID: 33115525
Background: Novel, less toxic, cost-effective and safe therapeutic strategies are needed to improve treatment of chronic lymphocytic leukemia (CLL). Ascorbic acid (AA, vitamin C) has shown a potential anti-cancer therapeutic...
7.
El Khayat El Sabbouri H, Gay-Queheillard J, Joumaa W, Delanaud S, Guibourdenche M, Darwiche W, et al.
Food Chem Toxicol
. 2020 Apr;
140:111322.
PMID: 32289335
The perinatal period is characterized by developmental stages with high sensitivity to environmental factors. Among the risk factors, maternal High-Fat Diet (HFD) consumption and early-life pesticide exposure can induce metabolic...
8.
Della-Valle V, Roos-Weil D, Scourzic L, Mouly E, Aid Z, Darwiche W, et al.
Blood Cancer J
. 2020 Mar;
10(3):38.
PMID: 32170099
Aberrant NF-κB activation is a hallmark of most B-cell malignancies. Recurrent inactivating somatic mutations in the NFKBIE gene, which encodes IκBε, an inhibitor of NF-κB-inducible activity, are reported in several...
9.
Chronic Lymphocytic Leukemia B-Cell Normal Cellular Counterpart: Clues From a Functional Perspective
Darwiche W, Gubler B, Marolleau J, Ghamlouch H
Front Immunol
. 2018 Apr;
9:683.
PMID: 29670635
Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of small mature-looking CD19+ CD23+ CD5+ B-cells that accumulate in the blood, bone marrow, and lymphoid organs. To date, no...
10.
Puy V, Darwiche W, Trudel S, Gomila C, Lony C, Puy L, et al.
Glia
. 2018 Apr;
66(8):1709-1723.
PMID: 29624734
Neuroinflammation and iron accumulation are hallmarks of a variety of adult neurodegenerative diseases. In Sanfilippo syndrome (mucopolysaccharidosis type III, MPSIII, a pediatric neurodegenerative disease that shares some features with adult...