Wairimu Chege
Overview
Explore the profile of Wairimu Chege including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
1136
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Recent Articles
1.
Pharmacologic Drug Detection and Self-Reported Adherence in the HPTN069/ACTG5305 Phase II PrEP Trial
Cooper S, Zhang S, Haines D, Mayer K, Amico K, Landovitz R, et al.
AIDS Behav
. 2024 Jul;
28(11):3710-3718.
PMID: 39083151
Adherence drives efficacy in PrEP clinical trials. We compared drug concentrations and self-reported adherence in HPTN069/ACTG5305, a double-blinded, randomized trial of the safety and tolerability of candidate PrEP regimens that...
2.
Walsh S, Gay C, Karuna S, Hyrien O, Skalland T, Mayer K, et al.
PLoS Med
. 2024 Jun;
21(6):e1004329.
PMID: 38913710
Background: Broadly neutralizing antibodies (bnAbs) are a promising approach for HIV-1 prevention. In the Antibody Mediated Prevention (AMP) trials, a CD4-binding site targeting bnAb, VRC01, administered intravenously (IV), demonstrated 75%...
3.
Walsh S, Gay C, Karuna S, Hyrien O, Skalland T, Mayer K, et al.
medRxiv
. 2024 Jan;
PMID: 38260276
Background: Broadly neutralizing antibodies (bnAbs) are a promising approach for HIV-1 prevention. In the only bnAb HIV prevention efficacy studies to date, the Antibody Mediated Prevention (AMP) trials, a CD4-binding...
4.
Sobieszczyk M, Mannheimer S, Paez C, Yu C, Gamble T, Theodore D, et al.
Lancet HIV
. 2023 Oct;
10(10):e653-e662.
PMID: 37802566
Background: Preclinical and clinical studies suggest that combinations of broadly neutralising antibodies (bnAbs) targeting different HIV envelope epitopes might be required for sufficient prevention of infection. We aimed to evaluate...
5.
Hamilton D, Agutu C, Sirengo M, Chege W, Goodreau S, Elder A, et al.
Epidemics
. 2023 Jun;
44:100696.
PMID: 37390706
Background: Up to 69% of adults who acquire HIV in Kenya seek care for acute retroviral symptoms, providing an important opportunity for early diagnosis and HIV care engagement. The Tambua...
6.
Mbilizi Chimwaza Y, Dadabhai S, Nyondo Mipando A, Mbeda C, Panchia R, Lucas J, et al.
PLOS Glob Public Health
. 2023 Mar;
2(12):e0001408.
PMID: 36962926
There remains a limited understanding of how men who have sex with men (MSM) and transgender women (TGW) in sub-Saharan Africa (SSA) perceive their risk for HIV and how risk...
7.
Babigumira J, Agutu C, Hamilton D, van der Elst E, Hassan A, Gichuru E, et al.
BMJ Open
. 2022 Sep;
12(9):e058636.
PMID: 36175097
Background: Detection of acute and prevalent HIV infection using point-of-care nucleic acid amplification testing (POC-NAAT) among outpatients with symptoms compatible with acute HIV is critical to HIV prevention, but it...
8.
Mayer K, Yuhas K, Amico K, Wilkin T, Landovitz R, Richardson P, et al.
AIDS Behav
. 2022 Jun;
26(12):4107-4114.
PMID: 35687192
HPTN 069/ACTG 5305 was designed to evaluate potential new PrEP regimens that included maraviroc, tenofovir disoproxil fumarate, and/or emtricitabine. The current analyses assessed antiretroviral (ARV) plasma concentrations in relation to...
9.
Hamilton D, Agutu C, Babigumira J, van der Elst E, Hassan A, Gichuru E, et al.
J Acquir Immune Defic Syndr
. 2022 May;
90(5):553-561.
PMID: 35510854
Background: Up to 69% of adults who acquire HIV in Kenya seek care before seroconversion, providing an important opportunity for early diagnosis and treatment. The Tambua Mapema Plus (TMP) trial...
10.
Agutu C, Oduor T, Hassan A, Mugo P, Chege W, Wit T, et al.
BMC Public Health
. 2022 Feb;
22(1):280.
PMID: 35148720
Background: HIV testing is the first step to stop transmission. We aimed to evaluate HIV testing history and new diagnoses among adult outpatients in Kenya aged 18-39 years seeking care...