W W Leitner
Overview
Explore the profile of W W Leitner including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
1236
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Recent Articles
1.
Diebold S, Schulz O, Alexopoulou L, Leitner W, Flavell R, Reis e Sousa C
Gene Ther
. 2008 Dec;
16(3):359-66.
PMID: 19052633
Replicon plasmids encoding an alphavirus RNA replicase constitute an alternative to conventional DNA plasmids with promise for DNA vaccination in humans. Replicase activity amplifies the levels of transgene mRNA through...
2.
Scheiblhofer S, Gabler M, Leitner W, Bauer R, Zoegg T, Ferreira F, et al.
Allergy
. 2006 Jun;
61(7):828-35.
PMID: 16792580
Background: Allergic diseases have become a major public health problem in developed countries; yet, no reliable, safe and consistently effective treatment is available. DNA immunization has been shown to prevent...
3.
Touloukian C, Leitner W, Robbins P, Rosenberg S, Restifo N
Cancer Res
. 2001 Nov;
61(22):8100-4.
PMID: 11719435
To identify novel, tumor-specific target antigens for vaccine development, we studied immune responses to P.polypeptide, an M(r) 110,000 integral melanosomal membrane protein associated with the Prader-Willi syndrome. Together with expressed...
4.
Frank S, Gaume B, Bergmann-Leitner E, Leitner W, Robert E, Catez F, et al.
Dev Cell
. 2001 Nov;
1(4):515-25.
PMID: 11703942
In healthy cells, fusion and fission events participate in regulating mitochondrial morphology. Disintegration of the mitochondrial reticulum into multiple punctiform organelles during apoptosis led us to examine the role of...
5.
Leitner W, Hammerl P, Thalhamer J
Curr Pharm Des
. 2001 Sep;
7(16):1641-67.
PMID: 11562304
Despite some interesting pilot experiments more than a century ago, nucleic acid has only recently been added to the list of agents used for the prevention and therapy of cancer....
6.
7.
Scheiblhofer S, Chen D, Weiss R, Khan F, Mostbock S, Fegeding K, et al.
Eur J Immunol
. 2001 Mar;
31(3):692-8.
PMID: 11241272
The C terminus of the circumsporozoite protein (CSP) is anchored to the parasite cell membrane by a glycosylphosphatidylinositol (GPI) glycolipid. This GPI signal sequence functions poorly in heterologous eukaryotic cells,...
8.
Weiss R, Leitner W, Scheiblhofer S, Chen D, Bernhaupt A, Mostbock S, et al.
Infect Immun
. 2000 Sep;
68(10):5914-9.
PMID: 10992502
The circumsporozoite protein (CSP) from the surface of sporozoite stage Plasmodium sp. malaria parasites is among the most important of the malaria vaccine candidates. Gene gun injection of genetic vaccines...
9.
Touloukian C, Leitner W, Topalian S, Li Y, Robbins P, Rosenberg S, et al.
J Immunol
. 2000 Mar;
164(7):3535-42.
PMID: 10725708
CD4+ T cells play a central role in the induction and persistence of CD8+ T cells in several models of autoimmune and infectious disease. To improve the efficacy of a...
10.
Restifo N, Ying H, Hwang L, Leitner W
Gene Ther
. 2000 Feb;
7(2):89-92.
PMID: 10673713
Establishing the effective use of 'naked' nucleic acids as vaccines would undoubtedly be one of the most important advances in the history of vaccinology. While nucleic acids show much promise...