W Robb MacLellan
Overview
Explore the profile of W Robb MacLellan including associated specialties, affiliations and a list of published articles.
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84
Citations
3059
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Recent Articles
1.
Li N, Nguyen B, Stitt Jr E, Zhang Z, MacLellan W, Zhang Y
Epigenomics
. 2024 Nov;
16(23-24):1407-1414.
PMID: 39601042
Background: Existing analyses with conventional assays have generated significant insights into static states of DNA methylation but were unable to visualize the dynamics of epigenetic regulation. Materials & Results: We...
2.
Li N, Nguyen B, Zhang Z, MacLellan W, Zhang Y
bioRxiv
. 2024 Jan;
PMID: 38293056
Background: Epigenetic DNA methylation is an essential mechanism controlling gene expression and cellular function. Existing analyses with conventional assays have generated significant insights into static states of DNA methylation, but...
3.
Marchiano S, Nakamura K, Reinecke H, Neidig L, Lai M, Kadota S, et al.
Cell Stem Cell
. 2023 May;
30(5):741.
PMID: 37146587
No abstract available.
4.
Marchiano S, Nakamura K, Reinecke H, Neidig L, Lai M, Kadota S, et al.
Cell Stem Cell
. 2023 Apr;
30(4):396-414.e9.
PMID: 37028405
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) offer a promising cell-based therapy for myocardial infarction. However, the presence of transitory ventricular arrhythmias, termed engraftment arrhythmias (EAs), hampers clinical applications. We hypothesized...
5.
Zhang Z, Freeman M, Zhang Y, El-Nachef D, Davenport G, Williams A, et al.
PLoS One
. 2023 Feb;
18(2):e0281610.
PMID: 36780463
Aims: Accumulating data demonstrates that new adult cardiomyocytes (CMs) are generated throughout life from pre-existing CMs, although the absolute magnitude of CM self-renewal is very low. Modifying epigenetic histone modifications...
6.
El-Nachef D, Martinson A, Yang X, Murry C, MacLellan W
Int J Cardiol Cardiovasc Dis
. 2022 Mar;
1(1):1-14.
PMID: 35243481
Histological analysis of fluorescently labeled tissues has been a critical tool to understand molecular organization . However, assessing molecular structures within large cells and in the context of human organ...
7.
Nakamura K, Neidig L, Yang X, Weber G, El-Nachef D, Tsuchida H, et al.
Stem Cell Reports
. 2021 Sep;
16(10):2473-2487.
PMID: 34506727
Heart failure remains a significant cause of morbidity and mortality following myocardial infarction. Cardiac remuscularization with transplantation of human pluripotent stem cell-derived cardiomyocytes is a promising preclinical therapy to restore...
8.
Gluck J, Chyu J, Delman C, Heydarkhan-Hagvall S, MacLellan W, Shemin R
ISRN Tissue Eng
. 2021 Jan;
2013.
PMID: 33426049
The relationship between stem cell niches and their surrounding microenvironment is still relatively unknown. Recent advances have indicated that extrinsic factors within the cardiovascular progenitor cell niche influence maintenance of...
9.
10.
Liu Y, Chen B, Yang X, Fugate J, Kalucki F, Futakuchi-Tsuchida A, et al.
Nat Biotechnol
. 2018 Sep;
36(9):899.
PMID: 30188532
No abstract available.