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W R Giles

Explore the profile of W R Giles including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 104
Citations 2803
Followers 0
Related Specialties
Physiology
Cardiology & Vascular Diseases
Cell Biology
Top 10 Co-Authors
R B Clark
J W Clark
E F Shibata
Y Imaizumi
C A Ward
Y Shimoni
D Fedida
C Fiset
A Nygren
D L Campbell
Published In
J Physiol
Am J Physiol
Circ Res
Am J Physiol Heart Circ Physiol
Math Biosci
Affiliations
Soon will be listed here.
Recent Articles
1.
The zebrafish atrioventricular canal: A model for mammalian AV node conduction and secondary or follower pacemaker activity
Giles W
Acta Physiol (Oxf) . 2024 Jan; 240(3):e14105. PMID: 38270514
No abstract available.
2.
Increases in dietary phosphate levels can augment atrial arrhythmias
Ganesan P, Narayan S, Giles W
Acta Physiol (Oxf) . 2023 Apr; 238(2):e13978. PMID: 37062019
No abstract available.
3.
Novel regulation of the mammalian cardiac Na channel by dipeptidyl peptidase 10 interactions: An editorial comment
Ni H, Rajamani S, Giles W
Int J Cardiol . 2019 Mar; 284:74-76. PMID: 30827732
No abstract available.
4.
ATP triggers a robust intracellular [Ca ]-mediated signalling pathway in human synovial fibroblasts
Kondo C, Clark R, AlJezani N, Kim T, Belke D, Banderali U, et al.
Exp Physiol . 2018 May; 103(8):1101-1122. PMID: 29791754
New Findings: What is the central question of this study? What are the main [Ca ] signalling pathways activated by ATP in human synovial fibroblasts? What is the main finding...
5.
Can principles of the surface potential be combined with knowledge of natural products to reduce atrial rhythm disturbances?
Ni H, Narsingani K, Zhang H, Giles W
Acta Physiol (Oxf) . 2017 Jul; 222(1). PMID: 28719150
No abstract available.
6.
Current-Voltage Relationship for Late Na(+) Current in Adult Rat Ventricular Myocytes
Clark R, Giles W
Curr Top Membr . 2016 Sep; 78:451-78. PMID: 27586292
It is now well established that the slowly inactivating component of the Na(+) current (INa-L) in the mammalian heart is a significant regulator of the action potential waveform. This insight...
7.
Cellular electrophysiological principles that modulate secretion from synovial fibroblasts
Clark R, Schmidt T, Sachse F, Boyle D, Firestein G, Giles W
J Physiol . 2016 Apr; 595(3):635-645. PMID: 27079855
Rheumatoid arthritis (RA) is a progressive disease that affects both pediatric and adult populations. The cellular basis for RA has been investigated extensively using animal models, human tissues and isolated...
8.
Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing
Quinn T, Granite S, Allessie M, Antzelevitch C, Bollensdorff C, Bub G, et al.
Prog Biophys Mol Biol . 2011 Jul; 107(1):4-10. PMID: 21745496
Cardiac experimental electrophysiology is in need of a well-defined Minimum Information Standard for recording, annotating, and reporting experimental data. As a step towards establishing this, we present a draft standard,...
9.
Blockade of K(ATP) channels reduces endothelial hyperpolarization and leukocyte recruitment upon reperfusion after hypoxia
Figura M, Chilton L, Liacini A, Viskovic M, Phan V, Knight D, et al.
Am J Transplant . 2009 Mar; 9(4):687-96. PMID: 19292831
Ischemia/reperfusion injury in renal transplantation leads to slow or initial nonfunction, and predisposes to acute and chronic rejection. In fact, severe ischemia reperfusion injury can significantly reduce graft survival, even...
10.
Optical mapping system for recording action potential durations in adult mouse left and right atrium
Nygren A, Lomax A, Giles W
Conf Proc IEEE Eng Med Biol Soc . 2007 Feb; 2004:3576-7. PMID: 17271063
The increasing availability of murine models of the cardiovascular system has created a need for instrumentation and methods for assessing murine cardiovascular function. We have adapted an existing optical mapping...