W Matthew Petroll
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Explore the profile of W Matthew Petroll including associated specialties, affiliations and a list of published articles.
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122
Citations
1952
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Recent Articles
1.
Poole K, Iyer K, Schmidtke D, Petroll W, Varner V
Invest Ophthalmol Vis Sci
. 2025 Mar;
66(3):28.
PMID: 40072446
Purpose: After stromal injury to the cornea, the release of growth factors and pro-inflammatory cytokines promotes the activation of quiescent keratocytes into a migratory fibroblast and/or fibrotic myofibroblast phenotype. Persistence...
2.
Subramanian D, Tjahjono N, Nammi S, Miron-Mendoza M, Varner V, Petroll W, et al.
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940950
Corneal fibroblasts are central to normal and abnormal wound healing in the cornea. During the wound healing process, several biochemical and biophysical signals that are present in the extracellular matrix...
3.
Iyer K, Maruri D, Schmidtke D, Petroll W, Varner V
bioRxiv
. 2024 Mar;
PMID: 38496568
Statement Of Significance: In vitro experiments have shown that changes in ECM stiffness can regulate the differentiation of myofibroblasts. Typically, these assays involve the use of individual growth factors, but...
4.
Poole K, Iyer K, Schmidtke D, Petroll W, Varner V
bioRxiv
. 2024 Mar;
PMID: 38464034
Purpose: After stromal injury to the cornea, the release of growth factors and pro-inflammatory cytokines promotes the activation of quiescent keratocytes into a migratory fibroblast and/or fibrotic myofibroblast phenotype. Persistence...
5.
Subramanian D, Tjahjono N, Hernandez P, Varner V, Petroll W, Schmidtke D
Langmuir
. 2024 Jan;
40(5):2551-2561.
PMID: 38277615
Many tissues in vivo contain aligned structures such as filaments, fibrils, and fibers, which expose cells to anisotropic structural and topographical cues that range from the nanometer to micrometer scales....
6.
Petroll W, Miron-Mendoza M, Sunkara Y, Ikebe H, Sripathi N, Hassaniardekani H
Exp Eye Res
. 2023 Jun;
233:109523.
PMID: 37271309
Previous studies have demonstrated that UV cross-linking (CXL) increases stromal stiffness and produces alterations in extracellular matrix (ECM) microstructure. In order to investigate how CXL impacts both keratocyte differentiation and...
7.
Effects of Topography and PDGF on the Response of Corneal Keratocytes to Fibronectin-Coated Surfaces
Lam K, Shihabeddin T, Awkal J, Najjar A, Miron-Mendoza M, Maruri D, et al.
J Funct Biomater
. 2023 Apr;
14(4).
PMID: 37103307
During corneal wound healing, corneal keratocytes are exposed to both biophysical and soluble cues that cause them to transform from a quiescent state to a repair phenotype. How keratocytes integrate...
8.
Mancini R, Forouzan P, Keenum Z, Tenzel P, Petroll W
Am J Ophthalmol
. 2023 Mar;
251:77-89.
PMID: 36898493
Purpose: Müller muscle-conjunctival resection (MMCR) is a popular posterior/internal surgical approach to cases of mild to moderate blepharoptosis with good levator function. MMCR necessitates the removal of healthy conjunctiva and...
9.
Gillings M, Mastro A, Zhang X, Kiser K, Gu J, Xing C, et al.
Ophthalmol Sci
. 2022 Oct;
3(1):100214.
PMID: 36275201
Objective: Seventy percent of Fuchs' endothelial corneal dystrophy (FECD) cases are caused by an intronic trinucleotide repeat expansion in the transcription factor 4 gene (). The objective of this study...
10.
McKay T, Kivanany P, Nicholas S, Nag O, Elliott M, Petroll W, et al.
Metabolites
. 2022 Jul;
12(7).
PMID: 35888751
We have previously reported the flavonoid, quercetin, as a metabolic regulator and inhibitor of myofibroblast differentiation in vitro. Our current study evaluated the effects of topical application of quercetin on...