W L Goff
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Explore the profile of W L Goff including associated specialties, affiliations and a list of published articles.
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59
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749
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Recent Articles
1.
Schneider D, Yan H, Bastos R, Johnson W, Gavin P, Allen A, et al.
Parasite Immunol
. 2010 Dec;
33(1):34-44.
PMID: 21155841
The spleen is a critical organ in defence against haemoparasitic diseases like babesiosis. Many in vitro and ex vivo studies have identified splenic cells working in concert to activate mechanisms...
2.
Goff W, Bastos R, Brown W, Johnson W, Schneider D
Vet Immunol Immunopathol
. 2010 Aug;
138(1-2):1-14.
PMID: 20692048
Over the past several years, innate immunity has been recognized as having an important role as a front-line defense mechanism and as an integral part of the adaptive immune response....
3.
Bastos R, Johnson W, Mwangi W, Brown W, Goff W
Vet Immunol Immunopathol
. 2008 Jun;
124(3-4):302-12.
PMID: 18514329
Early interactions of innate immune cell populations, such as dendritic cells (DC) and natural killer (NK) cells, can affect the ability of the acquired immune response to control infection of...
4.
Bastos R, Johnson W, Brown W, Goff W
Vet Immunol Immunopathol
. 2006 Dec;
115(3-4):334-45.
PMID: 17161869
Both bovine peripheral blood monocyte-derived dendritic cells (DC) and myeloid DC from afferent lymph have been described, but resident DC from other bovine tissues have not been fully characterized. The...
5.
Brown W, Norimine J, Goff W, Suarez C, Mcelwain T
Parasite Immunol
. 2006 Jul;
28(7):315-27.
PMID: 16842268
Babesial parasites infect cattle in tropical and temperate regions of the world and cause significant morbidity and mortality. Discovery of protective antigens that could be used in a killed vaccine...
6.
Goff W, Johnson W, HORN R, Barrington G, Knowles D
Parasite Immunol
. 2003 Aug;
25(4):185-8.
PMID: 12940961
The innate immune response to Babesia bovis infection in cattle is age-related, spleen-dependent and, in stabilate inoculated calves, has type-1 characteristics, including the early induction of IL-12 and IFN-gamma. In...
7.
Goff W, Johnson W, Tuo W, Valdez R, Parish S, Barrington G, et al.
Ann N Y Acad Sci
. 2002 Oct;
969:164-8.
PMID: 12381584
There is a strong innate immunity in calves to infection with Babesia bovis. Interleukin (IL)-12 and IL-10 have been shown in vitro to be important immunoregulatory cytokines. Here we demonstrate...
8.
Goff W, Johnson W, Parish S, Barrington G, Elsasser T, Davis W, et al.
Vet Immunol Immunopathol
. 2002 Jan;
84(3-4):237-51.
PMID: 11777537
The requirement for IFN-gamma and/or TNF-alpha as co-stimulants with Babesia bovis merozoites for nitric oxide (NO) production was examined, as well as the regulatory role of IL-4 and IL-10. Purified...
9.
Goff W, Johnson W, Parish S, Barrington G, Tuo W, Valdez R
Parasite Immunol
. 2001 Oct;
23(9):463-71.
PMID: 11589775
Young calves possess a strong innate immunity against Babesia bovis infection that lasts for approximately 6 months after birth and is abrogated with the removal of the spleen. This immunity...
10.
Rhalem A, Sahibi H, Lasri S, Johnson W, Kappmeyer L, Hamidouch A, et al.
J Vet Diagn Invest
. 2001 Aug;
13(3):249-51.
PMID: 11482604
A highly specific and sensitive competitive enzyme-linked immunosorbent assay for detection of specific antibody to Babesia equi in serum from equids was validated for use in Morocco. The assay is...