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W J McKenna

Explore the profile of W J McKenna including associated specialties, affiliations and a list of published articles. Areas
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Articles 338
Citations 7663
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Recent Articles
1.
Maruthappu T, Posafalvi A, Castelletti S, Delaney P, Syrris P, OToole E, et al.
Br J Dermatol . 2018 Nov; 180(5):1114-1122. PMID: 30382575
Background: Arrhythmogenic cardiomyopathy (AC) is an inherited, frequently underdiagnosed disorder, which can predispose individuals to sudden cardiac death. Rare, recessive forms of AC can be associated with woolly hair and...
2.
Lopes L, Murphy C, Syrris P, Dalageorgou C, McKenna W, Elliott P, et al.
Eur J Med Genet . 2015 Oct; 58(11):611-6. PMID: 26455666
Introduction: The role of copy-number variants (CNV) as a cause of hypertrophic cardiomyopathy (HCM) is poorly studied. The aim of this study was to use high-throughput sequence (HTS) data combined...
3.
Cox A, White S, Ayalew Y, Boos C, Haworth K, McKenna W
J R Army Med Corps . 2015 Aug; 161(3):275-82. PMID: 26246350
Myocarditis, simply defined as inflammation of the heart muscle, is a commonly encountered cardiac disease in primary and secondary care, both in the UK and on Operational deployments. In the...
4.
Hodgkinson K, Connors S, Merner N, Haywood A, Young T, McKenna W, et al.
Clin Genet . 2012 Jun; 83(4):321-31. PMID: 22725725
To determine the phenotype and natural history of a founder genetic subtype of autosomal dominant arrhythmogenic right ventricular cardiomyopathy (ARVC) caused by a p.S358L mutation in TMEM43. The age of...
5.
Seebohm B, Matinmehr F, Kohler J, Francino A, Navarro-Lopez F, Perrot A, et al.
Biophys J . 2009 Aug; 97(3):806-24. PMID: 19651039
The ability of myosin to generate motile forces is based on elastic distortion of a structural element of the actomyosin complex (cross-bridge) that allows strain to develop before filament sliding....
6.
Lambiase P, Ahmed A, Ciaccio E, Brugada R, Lizotte E, Chaubey S, et al.
Circulation . 2009 Jul; 120(2):106-17, 1-4. PMID: 19564561
Background: Two principal mechanisms are thought to be responsible for Brugada syndrome (BS): (1) right ventricular (RV) conduction delay and (2) RV subepicardial action potential shortening. This in vivo high-density...
7.
Sen-Chowdhry S, Sevdalis E, Wage R, Mist B, Kilner P, McKenna W
Int J Clin Pract . 2009 Jan; 62(11):1803-7. PMID: 19143866
No abstract available.
8.
Simpson M, Mansour S, Ahnood D, Kalidas K, Patton M, McKenna W, et al.
Cardiology . 2008 Oct; 113(1):28-34. PMID: 18957847
Objectives: The phenotypic triad of arrhythmogenic right ventricular cardiomyopathy (ARVC) associated with palmoplantar keratoderma and woolly hair has been previously associated with homozygous mutations in both plakoglobin and desmoplakin, which...
9.
Prasad K, Williams L, Campbell R, Elliott P, McKenna W, Frenneaux M
Heart . 2008 Jul; 94(10):1312-7. PMID: 18653581
Symptoms of impaired consciousness (syncope and pre-syncope) occur in 15-25% of patients with hypertrophic cardiomyopathy (HCM).1 In young patients a history of recurrent syncope is associated with an increased risk...
10.
Watkins H, Ashrafian H, McKenna W
Heart . 2008 Jul; 94(10):1264-8. PMID: 18653576
No abstract available.