W Ernest Lyons
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Explore the profile of W Ernest Lyons including associated specialties, affiliations and a list of published articles.
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4
Citations
323
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Recent Articles
1.
Liu Y, Yoo M, Savonenko A, Stirling W, Price D, Borchelt D, et al.
J Neurosci
. 2008 Dec;
28(51):13805-14.
PMID: 19091971
beta-Amyloid (Abeta) pathology is an essential pathogenic component in Alzheimer's disease (AD). However, the significance of Abeta pathology, including Abeta deposits/oligomers and glial reactions, to neurodegeneration is unclear. In particular,...
2.
Szapacs M, Mathews T, Tessarollo L, Lyons W, Mamounas L, Andrews A
J Neurosci Methods
. 2004 Dec;
140(1-2):81-92.
PMID: 15589338
Serotonin (5-HT) has been proposed to promote neuronal plasticity during the treatment of mood and anxiety disorders and following neurodegenerative insult by altering the expression of critical genes including brain-derived...
3.
Liu I, Lyons W, Mamounas L, Thompson R
J Neurosci
. 2004 Sep;
24(36):7958-63.
PMID: 15356210
In this study, brain-derived neurotrophic factor (BDNF) heterozygous knock-outs were tested on fear conditioning, and their wild-type littermates were used as controls. Results showed that BDNF(+/-) mice are impaired in...
4.
Subramaniam J, Lyons W, Liu J, Bartnikas T, Rothstein J, Price D, et al.
Nat Neurosci
. 2002 Mar;
5(4):301-7.
PMID: 11889469
Copper-mediated oxidative damage is proposed to play a critical role in the pathogenesis of Cu/Zn superoxide dismutase (SOD1)-linked familial amyotrophic lateral sclerosis (FALS). We tested this hypothesis by ablating the...