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W DIENER

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Articles 33
Citations 55
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Recent Articles
1.
Holzhutter H, Genschow E, DIENER W, Schlede E
Arch Toxicol . 2003 May; 77(5):243-54. PMID: 12734637
The acute toxic class (ATC) methods were developed for determining LD(50)/LC(50) estimates of chemical substances with significantly fewer animals than needed when applying conventional LD(50)/LC(50) tests. The ATC methods are...
2.
Banerjea M, DIENER W, Kutschke G, Schneble H, Korinthenberg R, Sutor A
Neuropediatrics . 2002 Oct; 33(4):215-20. PMID: 12368993
Objective: To evaluate sodium valproate-induced hemostatic side effects in children. Methods: A variety of both pro- and anticoagulatory parameters were longitudinally investigated in 80 children before therapy and up to...
3.
DIENER W, Benninger C, Rating D, Unnebrink K, Stephani U, Ernst H, et al.
Neuropediatrics . 2000 Nov; 31(4):169-74. PMID: 11071139
Lennox-Gastaut syndrome (LGS) is one of the most severe types of childhood epilepsy. It is usually resistant to treatment and associated with mental retardation. To delineate the risk factors associated...
4.
DIENER W, Kayser D, Schlede E
Arch Toxicol . 1999 Feb; 72(12):751-62. PMID: 9950071
A dermal acute toxic class (ATC) method is presented with the use of significantly fewer animals in comparison with the classical dermal 50% lethal dose (LD50) test. The principle of...
5.
DIENER W, Sorni M, Ruile S, Rude P, Kruse R, Becker E, et al.
Brain Dev . 1998 Apr; 20(2):83-7. PMID: 9545177
Potassium bromide again is well known to be surprisingly effective in patients with severe myoclonic epilepsy in infants (SME). Rare side effects on the skin reappeared, such as the febrile...
6.
Schenkel M, DIENER W
Kinderkrankenschwester . 1998 Mar; 17(1):13-5. PMID: 9485812
No abstract available.
7.
DIENER W, Kayser D, Schlede E
Arch Toxicol . 1997 Jan; 71(9):537-49. PMID: 9285036
A method of inhalation acute toxic (ATC) classification is presented with the use of significantly fewer animals in comparison with the classical LC50 test. The principle of the inhalation ATC...
8.
DIENER W, Schlede E
Hum Exp Toxicol . 1996 Oct; 15(10):855-8. PMID: 8906436
No abstract available.
9.
DIENER W, Mischke U, Schlede E, Kayser D
Arch Toxicol . 1995 Jan; 69(10):729-34. PMID: 8572934
No abstract available.
10.
Schlede E, Mischke U, DIENER W, Kayser D
Arch Toxicol . 1995 Jan; 69(10):659-70. PMID: 8572922
An alternative to the oral LD50 test, the acute toxic class (ATC) method (oral), was validated with 20 substances in an international collaborative study with nine laboratories in five countries....