W C Knowler
Overview
Explore the profile of W C Knowler including associated specialties, affiliations and a list of published articles.
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Articles
255
Citations
9629
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Recent Articles
1.
Perreault L, Pan Q, Aroda V, Barrett-Connor E, Dabelea D, Dagogo-Jack S, et al.
Diabet Med
. 2017 Aug;
34(12):1747-1755.
PMID: 28833481
Aim: Approximately half of the participants in the Diabetes Prevention Outcomes Study (DPPOS) had diabetes after 15 years of follow-up, whereas nearly all the others remained with pre-diabetes. We examined...
2.
Rushing J, Wing R, Wadden T, Knowler W, Lawlor M, Evans M, et al.
Obes Sci Pract
. 2017 Apr;
3(1):15-24.
PMID: 28392928
Objective: The Action for Health in Diabetes (Look AHEAD) trial was a randomized controlled clinical trial to compare the effects of 10 years of intensive lifestyle intervention (ILI) with a...
3.
Vijayakumar P, Wheelock K, Kobes S, Nelson R, Hanson R, Knowler W, et al.
Pediatr Obes
. 2016 Dec;
13(2):94-102.
PMID: 27923101
Background And Objectives: Most studies describing childhood obesity in the United States are based on cross-sectional surveys and do not include substantial numbers of American Indians (AI). Secular trends in...
4.
Wheelock K, Fufaa G, Nelson R, Hanson R, Knowler W, Sinha M
Pediatr Obes
. 2016 May;
12(4):295-303.
PMID: 27170264
Background: Childhood obesity is associated with increased cardiometabolic risk. Objective: To study the relationship between body mass index (BMI) and cardiometabolic risk factors in American Indian children and adolescents. Methods:...
5.
Mather K, Kim C, Christophi C, Aroda V, Knowler W, Edelstein S, et al.
J Clin Endocrinol Metab
. 2015 Jul;
100(10):3778-86.
PMID: 26200237
Context: Steroid sex hormones and SHBG may modify metabolism and diabetes risk, with implications for sex-specific diabetes risk and effects of prevention interventions. Objective: This study aimed to evaluate the...
6.
Aroda V, Christophi C, Edelstein S, Zhang P, Herman W, Barrett-Connor E, et al.
J Clin Endocrinol Metab
. 2015 Feb;
100(4):1646-53.
PMID: 25706240
Context: Gestational diabetes (GDM) confers a high risk of type 2 diabetes. In the Diabetes Prevention Program (DPP), intensive lifestyle (ILS) and metformin prevented or delayed diabetes in women with...
7.
Dabelea D, Ma Y, Knowler W, Marcovina S, Saudek C, Arakaki R, et al.
Diabet Med
. 2014 Mar;
31(9):1064-8.
PMID: 24646311
Aims: To determine if the presence of diabetes autoantibodies predicts the development of diabetes among participants in the Diabetes Prevention Program. Methods: A total of 3050 participants were randomized into...
8.
Hohenadel M, Thearle M, Grice B, Huang H, Dai M, Tao Y, et al.
Int J Obes (Lond)
. 2013 Nov;
38(8):1068-74.
PMID: 24276017
Background: In rodents, hypothalamic brain-derived neurotrophic factor (BDNF) expression appears to be regulated by melanocortin-4 receptor (MC4R) activity. The impact of MC4R genetic variation on circulating BDNF in humans is...
9.
McCaffery J, Papandonatos G, Huggins G, Peter I, Kahn S, Knowler W, et al.
Int J Obes (Lond)
. 2013 May;
37(12):1545-52.
PMID: 23628854
Background: Genome-wide association studies have provided new insights into the genetic factors that contribute to the development of obesity. We hypothesized that these genetic markers would also predict magnitude of...
10.
Christophi C, Resnick H, Ratner R, Temprosa M, Fowler S, Knowler W, et al.
J Diabetes Complications
. 2012 Nov;
27(2):150-7.
PMID: 23140912
Aims: To examine the ability of fasting plasma glucose (FPG) and/or 2-h glucose to confirm diabetes and to determine the proportion of participants with HbA1c ≥6.5%. Methods: Diabetes confirmation rates...