W C Gorospe
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Explore the profile of W C Gorospe including associated specialties, affiliations and a list of published articles.
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24
Citations
170
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Recent Articles
1.
TIJERINA M, Gorospe W, Bowman K, Badamchian M, Goldstein A, Spangelo B
Neuroimmunomodulation
. 1997 May;
4(3):163-70.
PMID: 9500150
Thymosin fraction 5 (TF5) is a partially purified preparation of the bovine thymus possessing immunopotentiating properties. TF5 also stimulates the hypothalamic-pituitary-adrenal axis in vivo and anterior pituitary hormone release in...
2.
Spangelo B, Judd A, Call G, Zumwalt J, Gorospe W
Neuroimmunomodulation
. 1995 Sep;
2(5):299-312.
PMID: 8739203
Cytokines are soluble mediators of immune function that also regulate several endocrine systems. Interleukin-1 (IL-1), IL-6 and tumor necrosis factor-alpha (TNF alpha) each mediate certain aspects of inflammation. In addition,...
3.
Spangelo B, Gorospe W
Front Neuroendocrinol
. 1995 Jan;
16(1):1-22.
PMID: 7768320
A rapidly growing body of evidence reveals that complex networks of communication exist between the neuroendocrine and the immune systems. Essential to the maintenance and function of the immune-endocrine circuitry...
4.
Johnson K, Hughes Jr F, Fong Y, Mathur R, WILLIAMSON H, Gorospe W
Am J Reprod Immunol
. 1994 Mar;
31(2-3):163-8.
PMID: 8049025
Problem: The localization and biological effects of atrial natriuretic peptide (ANP) are not limited to cardiac tissue but extend to a number of extra-atrial tissues and organs, including the ovary....
5.
Gorospe W, Spangelo B
Biol Reprod
. 1993 Mar;
48(3):538-43.
PMID: 7680907
In the present study we examined the influence of FSH as well as a number of well-established cytokines on interleukin (IL)-6 by rat granulosa cells in culture. Increasing concentrations of...
6.
Gorospe W, Hughes Jr F, Spangelo B
Endocrinology
. 1992 Mar;
130(3):1750-2.
PMID: 1537322
Treatment of FSH-stimulated granulosa cells with increasing amounts of interleukin-6 (IL-6) caused a significant concentration-dependent suppression of progesterone biosynthesis. However, basal progesterone production in non-FSH-stimulated cells remained unresponsive to the...
7.
Hughes Jr F, Gorospe W
Endocrinology
. 1991 Nov;
129(5):2415-22.
PMID: 1935775
In the present study, we examined the possibility that granulosa cell death during ovarian follicular atresia occurs by apoptosis (programmed cell death). To investigate this possibility, atresia was induced in...
8.
Hughes Jr F, Pringle C, Gorospe W
Biol Reprod
. 1991 May;
44(5):922-6.
PMID: 1868149
We have previously demonstrated that a progestin-stimulatory factor(s) (PSF) is present in the supernate of concanavalin A-activated rat splenocytes. In the absence of FSH, PSF evokes dose-dependent increases in both...
9.
Hughes Jr F, Lane T, Chen T, Gorospe W
Biol Reprod
. 1990 Nov;
43(5):812-7.
PMID: 2127227
Recent evidence indicates that factors produced by immune cells (cytokines) may play a role in ovarian function. To explore this possibility, we examined the effects of conditioned medium obtained from...
10.
Kasson B, Gorospe W
Mol Cell Endocrinol
. 1989 Mar;
62(1):103-11.
PMID: 2501121
A growing body of evidence indicates that substances released by activated immune cells can directly influence the functions of various endocrine cells. In the present study, the direct in vitro...