W B Stallcup
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Explore the profile of W B Stallcup including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination
Kucharova K, Stallcup W
Neuroscience
. 2009 Dec;
166(1):185-94.
PMID: 20006679
The NG2 proteoglycan has been shown to promote proliferation and motility in a variety of cell types. The presence of NG2 on oligodendrocyte progenitor cells (OPCs) suggests that the proteoglycan...
2.
Chekenya M, Krakstad C, Svendsen A, Netland I, Staalesen V, Tysnes B, et al.
Oncogene
. 2008 May;
27(39):5182-94.
PMID: 18469852
Chemoresistance represents a major problem in the treatment of many malignancies. Overcoming this obstacle will require improved understanding of the mechanisms responsible for this phenomenon. The progenitor cell marker NG2/melanoma...
3.
Joo N, Watanabe T, Chen C, Chekenya M, Stallcup W, Kapila Y
Cell Death Differ
. 2008 Feb;
15(5):899-907.
PMID: 18292781
Disruption of cell-matrix interactions can lead to anoikis - apoptosis due to loss of matrix contacts. Altered fibronectin (FN) induces anoikis of primary human fibroblasts by a novel signaling pathway...
4.
Rezajooi K, Pavlides M, Winterbottom J, Stallcup W, Hamlyn P, Lieberman A, et al.
Mol Cell Neurosci
. 2004 Apr;
25(4):572-84.
PMID: 15080887
The chondroitin sulphate proteoglycan NG2 blocks neurite outgrowth in vitro and thus may be able to inhibit axonal regeneration in the CNS. We have used immunohistochemistry to compare the expression...
5.
Ozerdem U, Grako K, Monosov E, Stallcup W
Dev Dyn
. 2001 Oct;
222(2):218-27.
PMID: 11668599
Immunofluorescence mapping demonstrates that the NG2 proteoglycan is invariably expressed by the mural cell component of mouse neovascular structures. This pattern is independent of the developmental mechanism responsible for formation...
6.
Lahdenranta J, Pasqualini R, Schlingemann R, Hagedorn M, Stallcup W, Bucana C, et al.
Proc Natl Acad Sci U S A
. 2001 Aug;
98(18):10368-73.
PMID: 11526242
Abnormal angiogenesis accompanies many pathological conditions including cancer, inflammation, and eye diseases. Proliferative retinopathy because of retinal neovascularization is a leading cause of blindness in developed countries. Another major cause...
7.
Stallcup W
J Cell Sci
. 2001 Aug;
114(Pt 12):2315-25.
PMID: 11493670
Targeting of the NG2 proteoglycan to cellular retraction fibers was studied by expressing mutant NG2 molecules lacking specific structural elements of the proteoglycan. Both the cytoplasmic domain and the chondroitin...
8.
Barritt D, Pearn M, Zisch A, Lee S, Javier R, Pasquale E, et al.
J Cell Biochem
. 2000 Sep;
79(2):213-24.
PMID: 10967549
A yeast two-hybrid screen was employed to identify ligands for the cytoplasmic domain of the NG2 chondroitin sulfate proteoglycan. Two overlapping cDNA clones selected in the screen are identical in...
9.
Goretzki L, Lombardo C, Stallcup W
J Biol Chem
. 2000 Jul;
275(37):28625-33.
PMID: 10889192
Interactions of the developmentally regulated chondroitin sulfate proteoglycan NG2 with human plasminogen and kringle domain-containing plasminogen fragments have been analyzed by solid-phase immunoassays and by surface plasmon resonance. In immunoassays,...
10.
Stallcup W
J Neurosci Res
. 2000 Jun;
61(1):33-43.
PMID: 10861797
As a means of defining functionally important regions of the L1 neuronal cell adhesion molecule, neurite outgrowth from cerebellar neurons was compared on monolayers of L1-negative B28 glioma cells, B28...