W B Fischer
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Explore the profile of W B Fischer including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
219
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Recent Articles
1.
Bichmann L, Wang Y, Fischer W
Comput Biol Chem
. 2017 Dec;
72:199.
PMID: 29248356
No abstract available.
2.
Kruger J, Fischer W
J Chem Theory Comput
. 2015 Dec;
5(9):2503-13.
PMID: 26616628
The generation of computational models is an alternative route to obtain reliable structures for the oligomeric state of membrane proteins. A strategy has been developed to search the conformational space...
3.
Mehnert T, Routh A, Judge P, Lam Y, Fischer D, Watts A, et al.
Proteins
. 2007 Oct;
70(4):1488-97.
PMID: 17910056
Vpu from HIV-1 is an 81 amino acid type I integral membrane protein which consists of a cytoplasmic and a transmembrane (TM) domain. The TM domain is known to alter...
4.
Mehnert T, Lam Y, Judge P, Routh A, Fischer D, Watts A, et al.
J Biomol Struct Dyn
. 2007 May;
24(6):589-96.
PMID: 17508781
Vpu, an integral membrane protein encoded in HIV-1, is implicated in the release of new virus particles from infected cells, presumably mediated by ion channel activity of homo-oligomeric Vpu bundles....
5.
Kim C, Lemaitre V, Watts A, Fischer W
Anal Bioanal Chem
. 2006 Nov;
386(7-8):2213-7.
PMID: 17082882
Vpu is an 81-amino-acid auxiliary protein of the genome of HIV-1. It is proposed that one of its roles is to enhance particle release by self-assembling to form water-filled channels...
6.
Lemaitre V, Willbold D, Watts A, Fischer W
J Biomol Struct Dyn
. 2006 Feb;
23(5):485-96.
PMID: 16494498
Based on structures made available by solution NMR, molecular models of the protein Vpu from HIV-1 were built and refined by 6 ns MD simulations in a fully hydrated lipid...
7.
Lemaitre V, Ali R, Kim C, Watts A, Fischer W
FEBS Lett
. 2004 Apr;
563(1-3):75-81.
PMID: 15063726
Vpu is an 81-residue membrane protein, with a single transmembrane segment that is encoded by HIV-1 and is involved in the enhancement of virion release via formation of an ion...
8.
Fischer W
FEBS Lett
. 2003 Sep;
552(1):39-46.
PMID: 12972150
Vpu is an 81 amino acid protein encoded by HIV-1. Its role is to amplify viral release by two mechanisms: (i) docking to CD4 with the consequence of targeting CD4...
9.
Sramala I, Lemaitre V, Faraldo-Gomez J, Vincent S, Watts A, Fischer W
Biophys J
. 2003 Apr;
84(5):3276-84.
PMID: 12719257
Vpu is an 81 amino acid protein of HIV-1 with two phosphorylation sites. It consists of a short N-terminal end traversing the bilayer and a longer cytoplasmic part. The dual...
10.
Cordes F, Tustian A, Sansom M, Watts A, Fischer W
Biochemistry
. 2002 Jun;
41(23):7359-65.
PMID: 12044168
Part of the genome of the human immunodeficiency virus type 1 (HIV-1) encodes for a short membrane protein Vpu, which has a length of 81 amino acids. It has two...