Volkan I Sayin
Overview
Explore the profile of Volkan I Sayin including associated specialties, affiliations and a list of published articles.
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35
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2132
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Recent Articles
1.
Eklund E, Svensson J, Naslund L, Yhr M, Sayin S, Wiel C, et al.
J Exp Clin Cancer Res
. 2025 Feb;
44(1):75.
PMID: 40011914
Background: In non-small cell lung cancer (NSCLC), the rapid advancement of predictive genetic testing of tumors by identifying specific pathogenic driver variants has significantly improved treatment guidance. However, immune checkpoint...
2.
Eklund E, Mourad A, Wiel C, Sayin S, Fagman H, Hallqvist A, et al.
Front Oncol
. 2024 Jun;
14:1396285.
PMID: 38884086
Background: mutation status is a well-established independent prognostic factor in advanced non-small cell lung cancer (NSCLC), yet its role in early-stage disease is unclear. Here, we investigate the prognostic value...
3.
Pillai R, LeBoeuf S, Hao Y, New C, Blum J, Rashidfarrokhi A, et al.
Sci Adv
. 2024 Mar;
10(13):eadm9859.
PMID: 38536921
Loss-of-function mutations in frequently occur in lung cancer and are associated with poor prognosis and resistance to standard of care treatment, highlighting the need for the development of targeted therapies....
4.
Wu K, El Zowalaty A, Sayin V, Papagiannakopoulos T
Nat Cancer
. 2024 Mar;
5(3):384-399.
PMID: 38531982
Cellular redox homeostasis is an essential, dynamic process that ensures the balance between reducing and oxidizing reactions within cells and thus has implications across all areas of biology. Changes in...
5.
Petterson J, Mustafa D, Bandaru S, Eklund E, Hallqvist A, Sayin V, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474205
Pulmonary adenocarcinoma (ADC) is a very diverse disease, both genetically and histologically, which displays extensive intratumor heterogeneity with numerous acquired mutations. ADC is the most common type of lung cancer...
6.
Yao H, Chen X, Wang T, Kashif M, Qiao X, Tuksammel E, et al.
Cell Rep
. 2023 Aug;
42(8):112961.
PMID: 37561633
Refractory and relapsed B cell lymphomas are often driven by the difficult-to-target oncogene MYC. Here, we report that high MYC expression stimulates proliferation and protects B lymphoma cells from apoptosis...
7.
Pillai R, LeBoeuf S, Hao Y, New C, Blum J, Rashidfarrokhi A, et al.
bioRxiv
. 2023 Jul;
PMID: 37425844
Loss-of-function mutations in frequently occur in lung cancer and are associated with resistance to standard of care treatment, highlighting the need for the development of targeted therapies. We have previously...
8.
Schwarz M, Meyer C, Loser A, Lossow K, Hackler J, Ott C, et al.
Nat Commun
. 2023 Jun;
14(1):3479.
PMID: 37311819
Selenium homeostasis depends on hepatic biosynthesis of selenoprotein P (SELENOP) and SELENOP-mediated transport from the liver to e.g. the brain. In addition, the liver maintains copper homeostasis. Selenium and copper...
9.
Dutta N, Rohlin A, Eklund E, Magnusson M, Nilsson F, Akyurek L, et al.
Front Oncol
. 2023 Feb;
12:1073457.
PMID: 36844924
Objectives: Immunotherapy by blocking programmed death protein-1 (PD-1) or programmed death protein-ligand1 (PD-L1) with antibodies (PD-1 blockade) has revolutionized treatment options for patients with non-small cell lung cancer (NSCLC). However,...
10.
Moreno R, Casares L, Higgins M, Ali K, Honda T, Wiel C, et al.
Free Radic Biol Med
. 2022 Sep;
191:203-211.
PMID: 36084789
The transcription factor BACH1 regulates the expression of a variety of genes including genes involved in oxidative stress responses, inflammation, cell motility, cancer cell invasion and cancer metabolism. Based on...