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Vladimir Riazanski

Explore the profile of Vladimir Riazanski including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 162
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Recent Articles
1.
Tourkova I, Larrouture Q, Liu S, Luo J, Shipman K, Onwuka K, et al.
Bone Rep . 2024 Apr; 21:101763. PMID: 38666049
Acid transport is required for bone synthesis by osteoblasts. The osteoblast basolateral surface extrudes acid by Na/H exchange, but apical proton uptake is undefined. We found high expression of the...
2.
Riazanski V, Mauleon G, Zimnicka A, Chen S, Nelson D
iScience . 2022 Jan; 25(1):103636. PMID: 35024579
Acidification in intracellular organelles is tightly linked to the influx of Cl counteracting proton translocation by the electrogenic V-ATPase. We quantified the dynamics of Cl transfer accompanying cargo incorporation into...
3.
Riazanski V, Mauleon G, Lucas K, Walker S, Zimnicka A, McGrath J, et al.
Commun Biol . 2022 Jan; 5(1):13. PMID: 35013561
Extracellular vesicles (EVs) are cell-derived membranous structures carrying transmembrane proteins and luminal cargo. Their complex cargo requires pH stability in EVs while traversing diverse body fluids. We used a filtration-based...
4.
Larrouture Q, Tourkova I, Stolz D, Riazanski V, Onwuka K, Franks J, et al.
Biochem Biophys Res Commun . 2021 Oct; 580:14-19. PMID: 34607258
Osteoblasts in vivo form an epithelial-like layer with tight junctions between cells. Bone formation involves mineral transport into the matrix and acid transport to balance pH levels. To study the...
5.
Riazanski V, Sui Z, Nelson D
iScience . 2020 Nov; 23(11):101759. PMID: 33251491
The relative contribution of the two phagosomal catabolic processes, oxidative and metabolic, was assessed in the killing of in phagosomes of alveolar macrophages (AMs) from wild-type ( ) or NOX-defective...
6.
Schlesinger P, Braddock D, Larrouture Q, Ray E, Riazanski V, Nelson D, et al.
Bone . 2020 Aug; 141:115621. PMID: 32858255
Three physiologically mineralizing tissues - teeth, cartilage and bone - have critical common elements and important evolutionary relationships. Phylogenetically the most ancient densely mineralized tissue is teeth. In jawless fishes...
7.
Schlesinger P, Blair H, Stolz D, Riazanski V, Ray E, Tourkova I, et al.
Am J Physiol Cell Physiol . 2019 Sep; 318(1):C111-C124. PMID: 31532718
Bone differs from other connective tissues; it is isolated by a layer of osteoblasts that are connected by tight and gap junctions. This allows bone to create dense lamellar type...
8.
Meijer L, Nelson D, Riazanski V, Gabdoulkhakova A, Hery-Arnaud G, Le Berre R, et al.
J Innate Immun . 2016 Mar; 8(4):330-49. PMID: 26987072
(R)-Roscovitine, a pharmacological inhibitor of kinases, is currently in phase II clinical trial as a drug candidate for the treatment of cancers, Cushing's disease and rheumatoid arthritis. We here review...
9.
Riazanski V, Gabdoulkhakova A, Boynton L, Eguchi R, Deriy L, Hogarth D, et al.
Proc Natl Acad Sci U S A . 2015 Nov; 112(47):E6486-95. PMID: 26604306
Defects in the innate immune system in the lung with attendant bacterial infections contribute to lung tissue damage, respiratory insufficiency, and ultimately death in the pathogenesis of cystic fibrosis (CF)....
10.
Riazanski V, Deriy L, Shevchenko P, Le B, Gomez E, Nelson D
Nat Neurosci . 2011 Mar; 14(4):487-94. PMID: 21378974
The absence of the chloride channel CLC-3 in Clcn3(-/-) mice results in hippocampal degeneration with a distinct temporal-spatial sequence that resembles neuronal loss in temporal lobe epilepsy. We examined how...