Vladimir Chobot
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Explore the profile of Vladimir Chobot including associated specialties, affiliations and a list of published articles.
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26
Citations
360
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Recent Articles
1.
Kubicova L, Bachmann G, Weckwerth W, Chobot V
Cells
. 2022 Mar;
11(6).
PMID: 35326409
Catechin is an extensively investigated plant flavan-3-ol with a beneficial impact on human health that is often associated with antioxidant activities and iron coordination complex formation. The aim of this...
2.
In Vitro Evaluation of Pro- and Antioxidant Effects of Flavonoid Tricetin in Comparison to Myricetin
Chobot V, Hadacek F, Bachmann G, Weckwerth W, Kubicova L
Molecules
. 2020 Dec;
25(24).
PMID: 33322312
Flavonoids are rather common plant phenolic constituents that are known for potent antioxidant effects and can be beneficial for human health. Flavonoids with a pyrogallol moiety are highly efficient reducing...
3.
Kubicova L, Chobot V
Neural Regen Res
. 2020 Aug;
16(2):308-309.
PMID: 32859788
No abstract available.
4.
Kubicova L, Hadacek F, Bachmann G, Weckwerth W, Chobot V
Antioxidants (Basel)
. 2019 Oct;
8(10).
PMID: 31614581
Reactive oxygen species (ROS) are known for their participation in various physiological and pathological processes in organisms, including ageing or degeneration. Kynurenine pathway metabolites, such as kynurenic (KYNA) or xanthurenic...
5.
Chobot V, Hadacek F, Bachmann G, Weckwerth W, Kubicova L
Int J Mol Sci
. 2018 Dec;
19(12).
PMID: 30544490
Background: The alkaloid 8-hydroxyquinoline (8HQ) is well-known for various biological activities, including antioxidant effects and especially for the formation of coordination complexes with various transition metals, such as iron, amongst...
6.
Chobot V, Hadacek F, Bachmann G, Weckwerth W, Kubicova L
Int J Mol Sci
. 2016 Nov;
17(12).
PMID: 27898046
The flavanol (±)-catechin shows an OH group but no 4-keto group on ring C (C3), and no conjugation between ring A and B. The related flavanone (+)-eriodictyol has a keto...
7.
Kubicova L, Hadacek F, Weckwerth W, Chobot V
J Organomet Chem
. 2015 Apr;
782:111-115.
PMID: 25892824
The tryptophan metabolite, quinolinic (2,3-pyridinedicarboxylic) acid, is known as an endogenous neurotoxin. Quinolinic acid can form coordination complexes with iron or copper. The effects of quinolinic acid on reactive oxygen...
8.
Chobot V, Hadacek F, Weckwerth W, Kubicova L
J Organomet Chem
. 2015 Apr;
782:103-110.
PMID: 25892823
Anthranilic acid (ANA) and 3-hydroxyanthranilic acid (3-HANA) are kynurenine pathway intermediates of the tryptophan metabolism. A hitherto unemployed method combination, differential pulse voltammetry, mass spectrometry (nano-ESI-MS), deoxyribose degradation and iron(II)...
9.
Chobot V, Hadacek F, Kubicova L
Molecules
. 2014 Dec;
19(12):20023-33.
PMID: 25470272
Iron is an essential co-factor for many enzymes that catalyze electron transfer reactions. It is well known that so-called "poorly liganded" iron can increase ROS concentrations and trigger oxidative stress...
10.
Kubicova L, Hadacek F, Chobot V
Int J Mol Sci
. 2013 Nov;
14(11):21328-38.
PMID: 24232578
Quinolinic acid (2,3-pyridinedicarboxylic acid, QUIN) is a well-known neurotoxin. Consequently, QUIN could produce reactive oxygen species (ROS). ROS are generated in reactions catalyzed by transition metals, especially iron (Fe). QUIN...