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Vladimir C Hachinski

Explore the profile of Vladimir C Hachinski including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 323
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Recent Articles
1.
Singh S, Zhong S, Rogers K, Hachinski V, Frisbee S
Arch Public Health . 2023 Aug; 81(1):158. PMID: 37620877
Introduction: This aim of this study is to provide updated estimates on the prevalence of dementia, heart disease, and stroke in Canadian communities. Targeting all three conditions together, at the...
2.
Roseborough A, Saad L, Goodman M, Cipriano L, Hachinski V, Whitehead S
Alzheimers Dement . 2022 Mar; 19(1):194-207. PMID: 35319162
Introduction: The primary aim of this paper is to improve the clinical interpretation of white matter hyperintensities (WMHs) and provide an overarching summary of methodological approaches, allowing researchers to design...
3.
Montero-Odasso M, Sarquis-Adamson Y, Speechley M, Borrie M, Hachinski V, Wells J, et al.
JAMA Neurol . 2017 May; 74(7):857-865. PMID: 28505243
Importance: Gait performance is affected by neurodegeneration in aging and has the potential to be used as a clinical marker for progression from mild cognitive impairment (MCI) to dementia. A...
4.
Weishaupt N, Riccio P, Dobbs T, Hachinski V, Whitehead S
Int J Mol Sci . 2015 Jun; 16(6):13921-36. PMID: 26090717
Subcortical ischemic strokes are among the leading causes of cognitive impairment. Selective atrophy of remote brain regions connected to the infarct is thought to contribute to deterioration of cognitive functions....
5.
Whitehead S, Massoni E, Cheng G, Hachinski V, Cimino M, Balduini W, et al.
Brain Res . 2010 Oct; 1366:246-56. PMID: 20934412
Clinical data has shown that stroke exacerbates dementia in Alzheimer's disease (AD) patients. Previous work, combining rat models of AD and stroke have shown that neuroinflammation may be the common...
6.
Whitehead S, Cheng G, Hachinski V, Cechetto D
Stroke . 2007 Oct; 38(12):3245-50. PMID: 17962591
Background And Purpose: In the elderly, cerebral ischemia (CI) occurs in the presence of high levels of amyloid. Neuroinflammation plays a critical role in the pathophysiology of Alzheimer's disease and...
7.
Whitehead S, Bayona N, Cheng G, Allen G, Hachinski V, Cechetto D
Stroke . 2006 Dec; 38(2):381-7. PMID: 17194886
Background And Purpose: Neuroinflammation plays a critical role in the pathogenesis of cerebral ischemia. Triflusal, a selective cyclooxygenase-2, and its active metabolite 3-hydroxy-4-trifluoromethylbenzoic acid may inhibit apoptosis and inflammation after...
8.
Ross J, Gross C, Desai M, Hong Y, Grant A, Daniels S, et al.
JAMA . 2006 Apr; 295(14):1675-80. PMID: 16609089
Context: Peer review should evaluate the merit and quality of abstracts but may be biased by geographic location or institutional prestige. The effectiveness of blinded peer review at reducing bias...
9.
Whitehead S, Hachinski V, Cechetto D
Stroke . 2004 Dec; 36(1):107-12. PMID: 15591213
Background And Purpose: Clinical data suggest that Alzheimer disease (AD) and stroke together potentiate cognitive impairment. Inflammatory mechanisms are involved in AD pathology and stroke and may be the mediator...
10.
Loscalzo J, Balaban R, Becker L, Ginsburg G, Hachinski V, Hall J, et al.
Circulation . 2002 Nov; 106(20):e149-61. PMID: 12427670
No abstract available.