Vladimir Bobkov
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Explore the profile of Vladimir Bobkov including associated specialties, affiliations and a list of published articles.
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14
Citations
191
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Recent Articles
1.
Perez Almeria C, Otun O, Schlimgen R, Lamme T, Crudden C, Youssef N, et al.
bioRxiv
. 2024 Nov;
PMID: 39574661
Chemokine stimulation of atypical chemokine receptor 3 (ACKR3) does not activate G proteins but recruits arrestins. It is a chemokine scavenger that indirectly influences responses by restricting the availability of...
2.
Anbuhl S, Dervillez X, Neubacher S, Schriek A, Bobkov V, de Taeye S, et al.
Biochem Pharmacol
. 2024 Aug;
227:116457.
PMID: 39098732
The chemokine receptor CXCR4 is involved in the development and migration of stem and immune cells but is also implicated in tumor progression and metastasis for a variety of cancers....
3.
Ma G, Crowley A, Heyndrickx L, Rogiers I, Parthoens E, Van Santbergen J, et al.
JCI Insight
. 2024 May;
9(10).
PMID: 38713534
The homeostasis of IgG is maintained by the neonatal Fc receptor, FcRn. Consequently, antagonism of FcRn to reduce endogenous IgG levels is an emerging strategy for treating antibody-mediated autoimmune disorders...
4.
Kleist A, Jenjak S, Sente A, Laskowski L, Szpakowska M, Calkins M, et al.
Science
. 2022 Jul;
377(6602):222-228.
PMID: 35857540
G protein-coupled receptors (GPCRs) recruit β-arrestins to coordinate diverse cellular processes, but the structural dynamics driving this process are poorly understood. Atypical chemokine receptors (ACKRs) are intrinsically biased GPCRs that...
5.
Zakrzewicz A, Wurth C, Beckert B, Feldhoff S, Vanderheyden K, Foss S, et al.
Cells
. 2022 May;
11(10).
PMID: 35626757
The authors wish to make the following changes to their paper [...].
6.
Zakrzewicz A, Wurth C, Beckert B, Feldhoff S, Vanderheyden K, Foss S, et al.
Cells
. 2022 Mar;
11(6).
PMID: 35326398
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister...
7.
Isbilir A, Moller J, Arimont M, Bobkov V, Perpina-Viciano C, Hoffmann C, et al.
Proc Natl Acad Sci U S A
. 2020 Nov;
117(46):29144-29154.
PMID: 33148803
Although class A G protein-coupled receptors (GPCRs) can function as monomers, many of them form dimers and oligomers, but the mechanisms and functional relevance of such oligomerization is ill understood....
8.
Hofland T, Endstra S, Gomes C, de Boer R, de Weerdt I, Bobkov V, et al.
Hemasphere
. 2020 Jan;
3(6):e308.
PMID: 31976482
Chronic lymphocytic leukemia (CLL) is characterized by an acquired immune dysfunction, which may underlie the hampered efficacy of cellular immunotherapy. Most data on dampened immune responses in CLL come from...
9.
Bobkov V, Arimont M, Zarca A, De Groof T, van der Woning B, de Haard H, et al.
Mol Pharmacol
. 2019 Sep;
96(6):753-764.
PMID: 31481460
Dysregulation of the chemokine system is implicated in a number of autoimmune and inflammatory diseases, as well as cancer. Modulation of chemokine receptor function is a very promising approach for...
10.
De Groof T, Bobkov V, Heukers R, Smit M
Mol Cell Endocrinol
. 2019 Jan;
484:15-24.
PMID: 30690070
The family of G protein-coupled receptors (GPCRs) is the largest class of membrane proteins and an important drug target due to their role in many (patho)physiological processes. Besides small molecules,...