Vladimir Bobek
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Explore the profile of Vladimir Bobek including associated specialties, affiliations and a list of published articles.
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64
Citations
799
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Recent Articles
1.
Klezl P, Svobodova P, Pospisilova E, Maly V, Bobek V, Kolostova K
Cell Mol Biol (Noisy-le-grand)
. 2024 Nov;
70(10):25-29.
PMID: 39605127
Circulating endometrial cells (CECs) have emerged as a new biomarker of advanced disease in women with endometriosis. The identification of several subtypes of CECs (e.g., stem cell-like, epithelial, glandular, stromal)...
2.
Miklovicova S, Volpini L, Sanovec O, Monaco F, Hadrava Vanova K, Novak J, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Nov;
1871(1):167556.
PMID: 39486656
Background: Renal cell carcinoma (RCC) is a disease typified by anomalies in cell metabolism. The function of mitochondria, including subunits of mitochondrial respiratory complex II (CII), in particular SDHB, are...
3.
Reginacova K, Pospisilova E, Kubecova M, Svobodova P, Bobek V, Kolostova K
Am J Cancer Res
. 2024 Aug;
14(7):3614-3625.
PMID: 39113856
Circulating tumor cells (CTCs) have significant potential to become an important tool for monitoring the effects of treatment in solid tumors. The present study reports the occurance of CTCs in...
4.
Bielcikova Z, Werner L, Stursa J, Cerny V, Krizova L, Spacek J, et al.
Ther Adv Med Oncol
. 2023 Oct;
15:17588359231197957.
PMID: 37786538
Mitochondrially targeted anticancer drugs (mitocans) that disrupt the energy-producing systems of cancer are emerging as new potential therapeutics. Mitochondrially targeted tamoxifen (MitoTam), an inhibitor of mitochondrial respiration respiratory complex I,...
5.
Bielcikova Z, Stursa J, Krizova L, Dong L, Spacek J, Hlousek S, et al.
EClinicalMedicine
. 2023 Apr;
57:101873.
PMID: 37064512
Background: Mitochondria present an emerging target for cancer treatment. We have investigated the effect of mitochondrially targeted tamoxifen (MitoTam), a first-in-class anti-cancer agent, in patients with solid metastatic tumours. Methods:...
6.
Immune activation of the monocyte-derived dendritic cells using patients own circulating tumor cells
Kolostova K, Pospisilova E, Matkowski R, Szelachowska J, Bobek V
Cancer Immunol Immunother
. 2022 Apr;
71(12):2901-2911.
PMID: 35471603
Background: Dendritic cell (DC) therapy counts to the promising strategies how to weaken and eradicate cancer disease. We aimed to develop a good manufacturing practice (GMP) protocol for monocyte-derived DC...
7.
Jakabova A, Bielcikova Z, Pospisilova E, Petruzelka L, Blasiak P, Bobek V, et al.
Ther Adv Med Oncol
. 2021 Aug;
13:17588359211028492.
PMID: 34345252
Background And Aims: The aim of this study was to characterize circulating tumor cells (CTCs) during neoadjuvant chemotherapy (NACT) in early and locally advanced breast cancer (LABC) patients. Using ultrasound,...
8.
Kolostova K, Pospisilova E, Pavlickova V, Bartos R, Sames M, Pawlak I, et al.
Am J Transl Res
. 2021 Jun;
13(5):4489-4499.
PMID: 34150029
Treatment of aggressive glioblastoma multiforme (GBM) must be based on very precise histological and molecular diagnostic of GBM type. According to the WHO guidelines, only tissue biopsy is a relevant...
9.
Klezl P, Pospisilova E, Kolostova K, Sonsky J, Maly O, Grill R, et al.
J Clin Med
. 2020 May;
9(5).
PMID: 32392757
The presence of circulating tumor cells (CTCs) in patients with solid tumors is associated with poor prognosis. However, there are limited data concerning the detection of CTCs in renal cell...
10.
Kiss I, Kolostova K, Pawlak I, Bobek V
J BUON
. 2020 Apr;
25(1):40-50.
PMID: 32277613
New non-invasive approaches have developed for diagnosis and treatment of malignant diseases. Cells shed from the primary tumor circulating in the bloodstream with metastasis potential are called Circulating Tumor Cells...