Vivian Wolfe
Overview
Explore the profile of Vivian Wolfe including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
125
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0
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Recent Articles
1.
Amman A, Wolfe V, Piraino G, Ziady A, Zingarelli B
Biomedicines
. 2024 Nov;
12(11).
PMID: 39595179
: The severity of acute lung injury is significantly impacted by age and sex in patients with hemorrhagic shock. AMP-activated protein kinase (AMPK) is a crucial regulator of energy metabolism...
2.
Wagner M, Ammann A, Piraino G, Wolfe V, OConnor M, Lahni P, et al.
Shock
. 2023 Apr;
60(1):64-74.
PMID: 37079467
Introduction: Despite therapeutic advances in hemorrhagic shock, mortality from multiple organ failure remains high. We previously showed that the α1 subunit of AMP-activated protein kinase (AMPK), a crucial regulator of...
3.
Davis X, Williamson L, Stuck J, Howell K, Lahni P, Piraino G, et al.
Shock
. 2023 Feb;
59(5):779-790.
PMID: 36840516
Introduction: Sepsis is a dysregulated host response to infection that can lead to life-threatening organ dysfunction. Clinical and animal studies consistently demonstrate that female subjects are less susceptible to the...
4.
Urban C, Hayes H, Piraino G, Wolfe V, Lahni P, OConnor M, et al.
Front Immunol
. 2022 Sep;
13:984298.
PMID: 36119052
Endothelial dysfunction plays a central role in the pathogenesis of sepsis-mediated multiple organ failure. Several clinical and experimental studies have suggested that the glycocalyx is an early target of endothelial...
5.
Hayes H, Wolfe V, OConnor M, Levinsky N, Piraino G, Zingarelli B
Int J Mol Sci
. 2021 Sep;
22(18).
PMID: 34576076
Mesenteric ischemia and reperfusion (I/R) injury can ensue from a variety of vascular diseases and represents a major cause of morbidity and mortality in intensive care units. It causes an...
6.
Wang P, Mu X, Zhao H, Li Y, Wang L, Wolfe V, et al.
Front Immunol
. 2021 Mar;
12:647070.
PMID: 33679812
The defective eradication of invading pathogens is a major cause of death in sepsis. As professional phagocytic cells, macrophages actively engulf/kill microorganisms and play essential roles in innate immune response...
7.
Kikuchi S, Piraino G, OConnor M, Wolfe V, Ridings K, Lahni P, et al.
Front Immunol
. 2020 Mar;
11:210.
PMID: 32117320
Alterations in the energy homeostasis contribute to sepsis-mediated multiple organ failure. The liver plays a central role in metabolism and participates to the innate immune and inflammatory responses of sepsis....
8.
Inata Y, Piraino G, Hake P, OConnor M, Lahni P, Wolfe V, et al.
Am J Physiol Heart Circ Physiol
. 2019 Apr;
316(4):H936-H937.
PMID: 30946605
No abstract available.
9.
Inata Y, Piraino G, Hake P, OConnor M, Lahni P, Wolfe V, et al.
Am J Physiol Heart Circ Physiol
. 2018 Jul;
315(4):H826-H837.
PMID: 29979626
Age represents a major risk factor for multiple organ failure, including cardiac dysfunction, in patients with sepsis. AMP-activated protein kinase (AMPK) is a crucial regulator of energy homeostasis that controls...
10.
Inata Y, Kikuchi S, Samraj R, Hake P, OConnor M, Ledford J, et al.
FASEB J
. 2017 Oct;
32(2):728-741.
PMID: 28974562
Age is an independent risk factor of multiple organ failure in patients with sepsis. However, the age-related mechanisms of injury are not known. AMPK is a crucial regulator of energy...