Vivek M Philip
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Explore the profile of Vivek M Philip including associated specialties, affiliations and a list of published articles.
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63
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1683
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Recent Articles
1.
Watts B, Smith C, Evans K, Gifford A, Mohamed S, Erickson S, et al.
Hemasphere
. 2025 Jan;
9(1):e70063.
PMID: 39830370
Antibody-drug conjugates (ADCs) combining monoclonal antibodies with cytotoxic payloads are a rapidly emerging class of immune-based therapeutics with the potential to improve the treatment of cancer, including children with relapse/refractory...
2.
Ball R, Bogue M, Liang H, Srivastava A, Ashbrook D, Lamoureux A, et al.
Genome Res
. 2024 Jan;
34(1):145-159.
PMID: 38290977
Hundreds of inbred mouse strains and intercross populations have been used to characterize the function of genetic variants that contribute to disease. Thousands of disease-relevant traits have been characterized in...
3.
Saul M, Litkowski E, Hadad N, Dunn A, Boas S, Wilcox J, et al.
bioRxiv
. 2024 Jan;
PMID: 38260300
Alzheimer's disease (AD) is a prevalent and costly age-related dementia. Heritable factors account for 58-79% of variation in late-onset AD, but substantial variation remains in age-of- onset, disease severity, and...
4.
Roy T, Bubier J, Dickson P, Wilcox T, Ndukum J, Clark J, et al.
Genes Brain Behav
. 2024 Jan;
:e12875.
PMID: 38164795
Substance use disorders are heritable disorders characterized by compulsive drug use, the biological mechanisms for which remain largely unknown. Genetic correlations reveal that predisposing drug-naïve phenotypes, including anxiety, depression, novelty...
5.
Ball R, Bogue M, Liang H, Srivastava A, Ashbrook D, Lamoureux A, et al.
bioRxiv
. 2023 Aug;
PMID: 37609331
Hundreds of inbred laboratory mouse strains and intercross populations have been used to functionalize genetic variants that contribute to disease. Thousands of disease relevant traits have been characterized in mice...
6.
Bogue M, Ball R, Walton D, Dunn M, Kolishovski G, Berger A, et al.
Mamm Genome
. 2023 Aug;
34(4):509-519.
PMID: 37581698
The Mouse Phenome Database continues to serve as a curated repository and analysis suite for measured attributes of members of diverse mouse populations. The repository includes annotation to community standard...
7.
Philip V, He H, Saul M, Dickson P, Bubier J, Chesler E
Sci Data
. 2023 Aug;
10(1):522.
PMID: 37543624
Brain transcriptional variation is a heritable trait that mediates complex behaviors, including addiction. Expression quantitative trait locus (eQTL) mapping reveals genomic regions harboring genetic variants that influence transcript abundance. In...
8.
Roy T, Bubier J, Dickson P, Wilcox T, Ndukum J, Clark J, et al.
bioRxiv
. 2023 Jul;
PMID: 37503148
Substance use disorders (SUDs) are heritable disorders characterized by compulsive drug use, but the biological mechanisms driving addiction remain largely unknown. Genetic correlations reveal that predisposing drug-naïve phenotypes, including anxiety,...
9.
Sproule T, Philip V, Chaudhry N, Roopenian D, Sundberg J
PLoS One
. 2023 Jul;
18(7):e0288263.
PMID: 37437067
Epidermolysis Bullosa (EB) is a group of rare genetic disorders that compromise the structural integrity of the skin such that blisters and subsequent erosions occur after minor trauma. While primary...
10.
Hughes K, Evans K, Earley E, Smith C, Erickson S, Stearns T, et al.
Pediatr Blood Cancer
. 2023 Jun;
:e30503.
PMID: 37339930
Background: While children with acute lymphoblastic leukemia (ALL) experience close to a 90% likelihood of cure, the outcome for certain high-risk pediatric ALL subtypes remains dismal. Spleen tyrosine kinase (SYK)...