Virginia M F Goncalves
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Explore the profile of Virginia M F Goncalves including associated specialties, affiliations and a list of published articles.
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24
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79
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Recent Articles
11.
Costa A, M F Goncalves V, Castro B, Carrola J, Langa I, Pereira A, et al.
Molecules
. 2023 Feb;
28(3).
PMID: 36771119
MDMA (3,4-methylenedioxymethamphetamine) is a chiral psychoactive recreational drug sold in illicit markets as racemate. Studies on the impact of MDMA on aquatic organisms are scarce. While enantioselectivity in toxicity in...
12.
Vieira S, M F Goncalves V, Llaguno C, Macias F, Tiritan M, Reis R, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36362404
Inflammatory diseases are the focus of several clinical studies, due to limitations and serious side effects of available therapies. Plant-based drugs (e.g., salicylic acid, morphine) have become landmarks in the...
13.
Gimondi S, Guimaraes C, Vieira S, M F Goncalves V, Tiritan M, Reis R, et al.
Nanomedicine
. 2021 Nov;
40:102482.
PMID: 34748958
In this study, a microfluidic device was employed to produce polymeric nanoparticles (NPs) with well-controlled sizes. The influence of several parameters in the synthesis process, namely, polymer concentration, flow rate...
14.
Sousa A, Ribeiro C, M F Goncalves V, Barbosa J, Peixoto B, Andrade A, et al.
J Pharm Biomed Anal
. 2021 Mar;
198:113997.
PMID: 33676170
Recent evidence indicates the relevant role of the tryptophan (TRP) metabolites in the pathophysiology of cardiovascular diseases via inflammatory and oxidative stress mechanisms. Therefore, quantification of TRP and its metabolites...
15.
Guedes M, Costa-Pinto A, M F Goncalves V, Moreira-Silva J, Tiritan M, Reis R, et al.
ACS Biomater Sci Eng
. 2021 Jan;
6(2):1017-1029.
PMID: 33464869
Sea-derived materials have promising applications in the medical, pharmaceutical, and biotechnological fields. Fish roe, for example, is a highly nutritional product, presenting diverse beneficial effects on human health. Therefore, this...
16.
Perez-Pereira A, Ribeiro C, Teles F, Goncalves R, M F Goncalves V, Pereira J, et al.
Environ Toxicol Chem
. 2020 Dec;
41(3):569-579.
PMID: 33289946
Ketamine is a chiral drug used for various clinical purposes but often misused. It is metabolized to norketamine, an active chiral metabolite. Both substances have been detected in environmental matrices,...
17.
Cartaxo A, Costa-Pinto A, Martins A, Faria S, M F Goncalves V, Tiritan M, et al.
J Biomed Mater Res A
. 2018 Nov;
107(3):482-493.
PMID: 30485652
Polymeric nanoparticles (NPs) are strong candidates for the development of systemic and targeted drug delivery applications. Their size is a determinant property since it defines the NP-cell interactions, drug loading...
18.
Silva M, Ribeiro C, M F Goncalves V, Tiritan M, Lima A
Biomed Chromatogr
. 2017 Dec;
32(5):e4159.
PMID: 29226354
Methotrexate (MTX) is an antifolate drug used for several diseases. Depending on the disease, MTX can be administered at low dose (LDMTX) in some autoimmune diseases, like rheumatoid arthritis, or...
19.
Sousa F, M F Goncalves V, Sarmento B
J Pharm Biomed Anal
. 2017 May;
142:171-177.
PMID: 28511059
Bevacizumab is a powerful human monoclonal antibody approved worldwide for treatment of several types of cancer and ocular diseases due to its potential as antiangiogenic drug. Nowadays, in order to...
20.
M F Goncalves V, Rodrigues P, Ribeiro C, Tiritan M
J Pharm Biomed Anal
. 2017 Apr;
141:1-8.
PMID: 28412606
A new two-dimensional liquid chromatography (2D-LC) method using a column switching valve, with a restricted-access media (RAM) column in the first dimension was developed and validated for the quantification of...