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Vinoj George

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Citations 378
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Recent Articles
1.
Wiseman J, Basit R, Suto A, Middya S, Kabiri B, Evans M, et al.
Neural Regen Res . 2025 Jan; PMID: 39820327
Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies. Biomaterial therapies show promise as medical materials for neural repair through immunomodulation, structural support, and...
2.
Barreto S, Hamel L, Schiatti T, Yang Y, George V
Cells . 2019 Dec; 8(12). PMID: 31795206
Cardiac Progenitor Cells (CPCs) show great potential as a cell resource for restoring cardiac function in patients affected by heart disease or heart failure. CPCs are proliferative and committed to...
3.
Duncan G, Firth K, George V, Duc Hoang M, Staniforth A, Smith G, et al.
Stem Cells Dev . 2017 Oct; 26(23):1695-1705. PMID: 28992755
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart. This is especially so for long QT syndrome...
4.
Rajamohan D, Kalra S, Duc Hoang M, George V, Staniforth A, Russell H, et al.
Stem Cells Dev . 2016 Feb; 25(6):439-52. PMID: 26906236
Automated planar patch clamp systems are widely used in drug evaluation studies because of their ability to provide accurate, reliable, and reproducible data in a high-throughput manner. Typically, CHO and...
5.
Denning C, Borgdorff V, Crutchley J, Firth K, George V, Kalra S, et al.
Biochim Biophys Acta . 2015 Nov; 1863(7 Pt B):1728-48. PMID: 26524115
Cardiomyocytes from human pluripotent stem cells (hPSCs-CMs) could revolutionise biomedicine. Global burden of heart failure will soon reach USD $90bn, while unexpected cardiotoxicity underlies 28% of drug withdrawals. Advances in...
6.
Dick E, Kalra S, Anderson D, George V, Ritso M, Laval S, et al.
Stem Cells Dev . 2013 Jul; 22(20):2714-24. PMID: 23829870
With an incidence of ∼1:3,500 to 5,000 in male children, Duchenne muscular dystrophy (DMD) is an X-linked disorder in which progressive muscle degeneration occurs and affected boys usually die in...
7.
Dick E, Kalra S, Anderson D, George V, Ritson M, Laval S, et al.
Stem Cells Dev . 2013 Jun; PMID: 23786351
With an incidence of ~1:3,500 to 5,000 in male children, Duchenne muscular dystrophy (DMD) is an X-linked disorder in which progressive muscle degeneration occurs and affected boys usually die in...
8.
Pascut F, Kalra S, George V, Welch N, Denning C, Notingher I
Biochim Biophys Acta . 2013 Feb; 1830(6):3517-24. PMID: 23403134
Background: Online label-free monitoring of in-vitro differentiation of stem cells remains a major challenge in stem cell research. In this paper we report the use of Raman micro-spectroscopy (RMS) to...
9.
Rajamohan D, Matsa E, Kalra S, Crutchley J, Patel A, George V, et al.
Bioessays . 2012 Aug; 35(3):281-98. PMID: 22886688
The emphasis in human pluripotent stem cell (hPSC) technologies has shifted from cell therapy to in vitro disease modelling and drug screening. This review examines why this shift has occurred,...
10.
Pascut F, Goh H, George V, Denning C, Notingher I
J Biomed Opt . 2011 May; 16(4):045002. PMID: 21529069
Raman micro-spectroscopy (RMS) has been recently proposed for label-free phenotypic identification of human embryonic stem cells (hESC)-derived cardiomyocytes. However, the methods used for measuring the Raman spectra led to acquisition...