Vinitha Denslin
Overview
Explore the profile of Vinitha Denslin including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
151
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Recent Articles
1.
Tee C, Roxby D, Othman R, Denslin V, Bhat K, Yang Z, et al.
Stem Cell Res Ther
. 2024 Nov;
15(1):403.
PMID: 39511618
No abstract available.
2.
Kang M, Yang Y, Zhang H, Zhang Y, Wu Y, Denslin V, et al.
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408956
Mesenchymal stromal cells (MSCs) are promising candidates for cartilage repair therapy due to their self-renewal, chondrogenic, and immunomodulatory capacities. It is widely recognized that a shift from fetal bovine serum...
3.
Tee C, Roxby D, Othman R, Denslin V, Bhat K, Yang Z, et al.
Stem Cell Res Ther
. 2024 Sep;
15(1):308.
PMID: 39285485
Background: Articular cartilage degeneration can result from injury, age, or arthritis, causing significant joint pain and disability without surgical intervention. Currently, the only FDA cell-based therapy for articular cartilage injury...
4.
Yang Z, Wu Y, Neo S, Yang D, Jeon H, Tee C, et al.
Am J Sports Med
. 2024 Jan;
52(2):503-515.
PMID: 38186352
Background: The functional heterogeneity of culture-expanded mesenchymal stem cells (MSCs) has hindered the clinical application of MSCs. Previous studies have shown that MSC subpopulations with superior chondrogenic capacity can be...
5.
Yang Y, Wu Y, Yang D, Neo S, Kadir N, Goh D, et al.
Bioact Mater
. 2023 Apr;
27:98-112.
PMID: 37006826
Secretome derived from mesenchymal stem cells (MSCs) have profound effects on tissue regeneration, which could become the basis of future MSCs therapies. Hypoxia, as the physiologic environment of MSCs, has...
6.
Kadir N, Yang Z, Hassan A, Denslin V, Lee E
Stem Cell Res Ther
. 2021 Feb;
12(1):100.
PMID: 33536060
Background: Secretome profiles of mesenchymal stem cells (MSCs) are reflective of their local microenvironments. These biologically active factors exert an impact on the surrounding cells, eliciting regenerative responses that create...
7.
Wu Y, Yang Z, Denslin V, Ren X, Lee C, Yap F, et al.
Am J Sports Med
. 2020 Mar;
48(7):1735-1747.
PMID: 32191492
Background: Articular cartilage has a zonal architecture and biphasic mechanical properties. The recapitulation of surface lubrication properties with high compressibility of the deeper layers of articular cartilage during regeneration is...
8.
Yin L, Yang Z, Wu Y, Denslin V, Yu C, Tee C, et al.
Biomaterials
. 2020 Feb;
240:119881.
PMID: 32092592
Mesenchymal stem cells (MSCs) have the capability to differentiate into multiple cell lineages, and produce trophic factors to facilitate tissue repair and regeneration, and disease regression. However, the heterogeneity of...
9.
Liu T, Yildirim E, Li P, Fang H, Denslin V, Kumar V, et al.
Stem Cell Reports
. 2020 Feb;
14(2):210-225.
PMID: 32004493
The effects of ascorbate on adult cell fate specification remain largely unknown. Using our stepwise and chemically defined system to derive lateral mesoderm progenitors from human pluripotent stem cells (hPSCs),...
10.
Yin L, Wu Y, Yang Z, Denslin V, Ren X, Tee C, et al.
Biomaterials
. 2018 Mar;
165:66-78.
PMID: 29518707
Current clinical approaches for articular cartilage repair have not been able to restore the tissue with zonal architecture, and its biomechanical and functional properties. Mimicking the zonal organization of articular...