Vincenzo Piccialli
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Explore the profile of Vincenzo Piccialli including associated specialties, affiliations and a list of published articles.
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36
Citations
214
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Recent Articles
1.
Morretta E, Capuano A, DUrso G, Voli A, Mozzicafreddo M, Di Gaetano S, et al.
Mar Drugs
. 2024 Feb;
22(2).
PMID: 38393023
Mycalin A (MA) is a polybrominated C-15 acetogenin isolated from the marine sponge . Since this substance displays a strong antiproliferative bioactivity towards some tumour cells, we have now directed...
2.
Capasso D, Marino P, Di Gaetano S, Borbone N, Terracciano M, Trani R, et al.
Mar Drugs
. 2023 Jun;
21(6).
PMID: 37367674
Starting from D-xylonolactone and D-ribonolactone, several five-membered bromolactones, related to the C1-C5 portion of mycalin A lactone, have been synthesized. The bromination of D-ribonolactone with HBr/AcOH, without a subsequent transesterification...
3.
Borbone N, Piccialli I, Falanga A, Piccialli V, Roviello G, Oliviero G
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35457177
The recent development of mRNA vaccines against the SARS-CoV-2 infection has turned the spotlight on the potential of nucleic acids as innovative prophylactic agents and as diagnostic and therapeutic tools....
4.
Capasso D, Borbone N, Terracciano M, Di Gaetano S, Piccialli V
Mar Drugs
. 2020 Aug;
18(8).
PMID: 32751383
Mycalin A, a polybrominated C acetogenin isolated from the encrusting sponge , displays an antiproliferative activity on human melanoma (A375) and cervical adenocarcinoma (HeLa) cells and induces cell death by...
5.
DErrico S, Basso E, Falanga A, Marzano M, Pozzan T, Piccialli V, et al.
Mar Drugs
. 2019 Aug;
17(8).
PMID: 31426471
Herein, we report on the synthesis of a small set of linear precursors of an inosine analogue of cyclic ADP-ribose (cADPR), a second messenger involved in Ca mobilization from ryanodine...
6.
Caso A, Mangoni A, Piccialli G, Costantino V, Piccialli V
ACS Omega
. 2018 Jul;
2(4):1477-1488.
PMID: 30023636
A chiral pool protocol toward the synthesis of the smenamide family of natural products is described. Two stereoisomers of smenamide A, namely, -smenamide A and 16--smenamide A were synthesized with...
7.
Caso A, Laurenzana I, Lamorte D, Trino S, Esposito G, Piccialli V, et al.
Mar Drugs
. 2018 Jun;
16(6).
PMID: 29899231
Smenamides are an intriguing class of peptide/polyketide molecules of marine origin showing antiproliferative activity against lung cancer Calu-1 cells at nanomolar concentrations through a clear pro-apoptotic mechanism. To probe the...
8.
Piccialli V, Tuzi A, Centore R
Acta Crystallogr E Crystallogr Commun
. 2017 Nov;
73(Pt 11):1603-1606.
PMID: 29152333
The title compound, CHO, is a polyoxygenated ep-oxy steroid obtained by a multi-step synthesis involving oxidation of 7-de-hydro-cholesterol. It crystallizes in the 222 space group; however, the absolute structure of...
9.
Piccialli V, Tuzi A, Centore R
Acta Crystallogr E Crystallogr Commun
. 2017 Sep;
73(Pt 9):1282-1286.
PMID: 28932455
The title compound, CHO, is one of the products obtained by oxidation of squalene with the catalytic system RuO(cat.)/NaIO. It crystallizes in the -1 space group, with four crystallographically independent...
10.
Piccialli V, Tuzi A, Centore R
Acta Crystallogr E Crystallogr Commun
. 2017 May;
73(Pt 5):780-784.
PMID: 28529798
The title compound, CHO, is a product of oxidation of squalene with the catalytic system RuO(cat.)/NaIO. The asymmetric unit contains two crystallographically independent mol-ecules of very similar geometry approximately related...