Vilde Kaldhusdal
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Explore the profile of Vilde Kaldhusdal including associated specialties, affiliations and a list of published articles.
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11
Citations
40
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Recent Articles
1.
Hasselrot T, Alvendal C, Hunt S, Boger M, Kaldhusdal V, Damdimopoulos A, et al.
Am J Reprod Immunol
. 2025 Jan;
93(1):e70040.
PMID: 39776248
Problem: Recurrent vulvovaginal candidiasis (RVVC) affects 5%-10% of all women, negatively impacting their reproductive health and quality of life. Herein, we investigated the molecular effects of RVVC on the vaginal...
2.
Kaldhusdal V, Boger M, Tjernlund A, Burgener A, Bradley F, Lajoie J, et al.
Sci Rep
. 2025 Jan;
15(1):1014.
PMID: 39762272
The injectable contraceptive, depot medroxyprogesterone acetate (DMPA), is associated with compromised cervical mucosal barriers. High-resolution spatial transcriptomics is applied here to reveal the spatial localization of these altered molecular markers....
3.
Boger M, Kaldhusdal V, Pascual-Reguant A, Kroh S, Uecker R, Burgener A, et al.
Front Immunol
. 2024 Dec;
15:1483346.
PMID: 39687623
Introduction: Chronic immune activation is a hallmark of human immunodeficiency virus (HIV) infection that significantly impacts disease pathogenesis. However, in-depth studies characterizing the immunological landscape of the ectocervix during chronic...
4.
Boger M, Hasselrot T, Kaldhusdal V, Miranda G, Czarnewski P, Edfeldt G, et al.
PLoS Pathog
. 2024 Nov;
20(11):e1012709.
PMID: 39561211
Chronic systemic immune activation significantly influences human immunodeficiency virus (HIV) disease progression. Despite evidence of a pro-inflammatory environment in the genital tract of HIV-infected women, comprehensive investigations into cervical tissue...
5.
Bradley F, Stern A, Boger M, Mousavian Z, Dethlefsen O, Kaldhusdal V, et al.
Front Endocrinol (Lausanne)
. 2024 Oct;
15:1454006.
PMID: 39439565
Background: The cervicovaginal epithelial barrier is crucial for defending the female reproductive tract against sexually transmitted infections. Hormones, specifically estradiol and progesterone, along with their respective receptor expressions, play an...
6.
Hugerth L, Krog M, Vomstein K, Du J, Bashir Z, Kaldhusdal V, et al.
Microbiome
. 2024 Aug;
12(1):153.
PMID: 39160615
Background: The composition of the vaginal microbiota during the menstrual cycle is dynamic, with some women remaining eu- or dysbiotic and others transitioning between these states. What defines these dynamics,...
7.
Edfeldt G, Kaldhusdal V, Czarnewski P, Bradley F, Bergstrom S, Lajoie J, et al.
Microbiome
. 2023 Apr;
11(1):67.
PMID: 37004130
Background: The majority of studies characterizing female genital tract microbiota have focused on luminal organisms, while the presence and impact of tissue-adherent ectocervical microbiota remain incompletely understood. Studies of luminal...
8.
Bradley F, Boger M, Kaldhusdal V, Ahlberg A, Edfeldt G, Lajoie J, et al.
PLoS Pathog
. 2022 May;
18(5):e1010494.
PMID: 35533147
Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used by millions of women worldwide. However, experimental studies have associated DMPA use with genital epithelial barrier disruption and mucosal influx...
9.
Gibbs A, Healy K, Kaldhusdal V, Sundling C, Franzen-Boger M, Edfeldt G, et al.
J Infect Dis
. 2022 May;
226(8):1428-1440.
PMID: 35511032
Background: Mucosa-associated invariant T (MAIT) cells are innate-like T cells with specialized antimicrobial functions. Circulating MAIT cells are depleted in chronic human immunodeficiency virus (HIV) infection, but studies examining this...
10.
Rohl M, Tjernlund A, Lajoie J, Edfeldt G, Bradley F, Bergstrom S, et al.
Vaccines (Basel)
. 2021 Apr;
9(3).
PMID: 33806390
Immunological correlates of natural resistance to HIV have been identified in HIV-exposed seronegative (HESN) individuals and include a low-inflammatory genital mucosal status. The cervicovaginal epithelium has not been studied for...