Viktoria Bojilova
Overview
Explore the profile of Viktoria Bojilova including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
250
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Recent Articles
1.
Ceglia N, Sethna Z, Freeman S, Uhlitz F, Bojilova V, Rusk N, et al.
Nat Commun
. 2023 Jul;
14(1):4400.
PMID: 37474509
Deciphering individual cell phenotypes from cell-specific transcriptional processes requires high dimensional single cell RNA sequencing. However, current dimensionality reduction methods aggregate sparse gene information across cells, without directly measuring the...
2.
Maron S, Chatila W, Walch H, Chou J, Ceglia N, Ptashkin R, et al.
Clin Cancer Res
. 2023 Jul;
29(18):3633-3640.
PMID: 37406106
Purpose: We report updated clinical outcomes from a phase II study of pembrolizumab, trastuzumab, and chemotherapy (PTC) in metastatic esophagogastric cancer in conjunction with outcomes from an independent Memorial Sloan...
3.
Shahid S, Ceglia N, Le Luduec J, McPherson A, Spitzer B, Kontopoulos T, et al.
Blood Adv
. 2023 Jun;
7(17):5069-5081.
PMID: 37327118
Although allogeneic hematopoietic cell transplant (allo-HCT) is curative for high-risk pediatric acute myeloid leukemia (AML), disease relapse remains the primary cause of posttransplant mortality. To identify pressures imposed by allo-HCT...
4.
Vazquez-Garcia I, Uhlitz F, Ceglia N, Lim J, Wu M, Mohibullah N, et al.
Nature
. 2022 Dec;
612(7941):778-786.
PMID: 36517593
High-grade serous ovarian cancer (HGSOC) is an archetypal cancer of genomic instability patterned by distinct mutational processes, tumour heterogeneity and intraperitoneal spread. Immunotherapies have had limited efficacy in HGSOC, highlighting...
5.
Funnell T, OFlanagan C, Williams M, McPherson A, McKinney S, Kabeer F, et al.
Nature
. 2022 Oct;
612(7938):106-115.
PMID: 36289342
How cell-to-cell copy number alterations that underpin genomic instability in human cancers drive genomic and phenotypic variation, and consequently the evolution of cancer, remains understudied. Here, by applying scaled single-cell...
6.
Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, et al.
Cell
. 2019 Nov;
179(5):1207-1221.e22.
PMID: 31730858
Accurate measurement of clonal genotypes, mutational processes, and replication states from individual tumor-cell genomes will facilitate improved understanding of tumor evolution. We have developed DLP+, a scalable single-cell whole-genome sequencing...