Vijaya Lakshmi Simhadri
Overview
Explore the profile of Vijaya Lakshmi Simhadri including associated specialties, affiliations and a list of published articles.
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5
Citations
371
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Recent Articles
1.
Hansen H, Engels H, Dams M, Paes Leme A, Pauletti B, Simhadri V, et al.
J Pathol
. 2014 Mar;
232(4):405-14.
PMID: 24659185
Classical Hodgkin's lymphoma (cHL)-affected lymphoid tissue contains only a few malignant Hodgkin and Reed-Sternberg (HRS) cells, which are disseminated within a massive infiltrate of reactive cells. In particular, the innate...
2.
Simhadri V, Hansen H, Simhadri V, Reiners K, Bessler M, Engert A, et al.
Biol Chem
. 2012 May;
393(1-2):101-6.
PMID: 22628304
The interplay between dendritic cells (DCs) and natural killer (NK) cells directs adaptive immune responses. The molecular basis of the cross-talk is largely undefined. Here, we provide evidence for a...
3.
Simhadri V, Reiners K, Hansen H, Topolar D, Simhadri V, Nohroudi K, et al.
PLoS One
. 2008 Oct;
3(10):e3377.
PMID: 18852879
NKp30, a natural cytotoxicity receptor expressed on NK cells is critically involved in direct cytotoxicity against various tumor cells and directs both maturation and selective killing of dendritic cells. Recently...
4.
Pogge von Strandmann E, Simhadri V, von Tresckow B, Sasse S, Reiners K, Hansen H, et al.
Immunity
. 2007 Dec;
27(6):965-74.
PMID: 18055229
The activity of natural killer (NK) cells is regulated by surface receptors, which direct target cell recognition. NKp30 (Natural Cytotoxicity Receptor 3) induces target cell lysis and is also crucial...
5.
Eichenauer D, Simhadri V, Pogge von Strandmann E, Ludwig A, Matthews V, Reiners K, et al.
Cancer Res
. 2007 Jan;
67(1):332-8.
PMID: 17210715
CD30 is a transmembrane protein selectively overexpressed on many human lymphoma cells and therefore an interesting target for antibody-based immunotherapy. However, binding of therapeutic antibodies stimulates a juxtamembrane cleavage of...