Victoria Lutgen
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Explore the profile of Victoria Lutgen including associated specialties, affiliations and a list of published articles.
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10
Citations
316
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Recent Articles
1.
Lutgen V, Narasipura S, Barbian H, Richards M, Wallace J, Razmpour R, et al.
PLoS Pathog
. 2020 Jun;
16(6):e1008381.
PMID: 32525948
HIV invades the brain during acute infection. Yet, it is unknown whether long-lived infected brain cells release productive virus that can egress from the brain to re-seed peripheral organs. This...
2.
Wallace J, Lutgen V, Avasarala S, St Croix B, Winn R, Al-Harthi L
Immunology
. 2017 Sep;
153(2):203-213.
PMID: 28872671
The variation of macrophage functions suggests the involvement of multiple signalling pathways in fine tuning their differentiation. Macrophages that originate from monocytes in the blood migrate to tissue in response...
3.
Lutgen V, Narasipura S, Sharma A, Min S, Al-Harthi L
J Neuroinflammation
. 2016 Sep;
13(1):242.
PMID: 27612942
Background: Neurological disorders have been linked to abnormal excitatory neurotransmission. Perturbations in glutamate cycling can have profound impacts on normal activity, lead to excitotoxicity and neuroinflammation, and induce and/or exacerbate...
4.
Richards M, Narasipura S, Seaton M, Lutgen V, Al-Harthi L
J Immunol
. 2015 Nov;
196(1):317-27.
PMID: 26582945
The role of CD8(+) T cells in HIV control in the brain and the consequences of such control are unclear. Approximately 3% of peripheral CD8(+) T cells dimly express CD4...
5.
Richards M, Narasipura S, Kim S, Seaton M, Lutgen V, Al-Harthi L
Glia
. 2014 Oct;
63(3):441-51.
PMID: 25331637
HIV-mediated neuropathogenesis is a multifaceted process involving several players, including resident brain cells (neurons, astrocytes, and microglia) and infiltrating cells [peripheral blood mononuclear cells (PBMCs)]. We evaluated the dynamic interaction...
6.
Lutgen V, Resch J, Qualmann K, Raddatz N, Panhans C, Olander E, et al.
Psychopharmacology (Berl)
. 2014 May;
231(24):4637-47.
PMID: 24828877
Rationale: Gaps in our understanding of glutamatergic signaling may be key obstacles in accurately modeling complex CNS diseases. System xc (-) is an example of a poorly understood component of...
7.
Lu R, Wu S, Zhang Y, Xia Y, Huelsmann E, Lacek A, et al.
AIDS Res Hum Retroviruses
. 2014 Mar;
30(7):677-84.
PMID: 24593860
HIV infection is a risk factor for the tumorigenesis including non-AIDS-defining cancers such as those of the gastrointestinal tract. However, the mechanisms underlying such cancer outgrowth are still unknown. Furthermore,...
8.
Lutgen V, Qualmann K, Resch J, Kong L, Choi S, Baker D
Psychopharmacology (Berl)
. 2012 Nov;
226(3):531-40.
PMID: 23192314
Rationale: Aspects of schizophrenia, including deficits in sensorimotor gating, have been linked to glutamate dysfunction and/or oxidative stress in the prefrontal cortex. System xc(-), a cystine-glutamate antiporter, is a poorly...
9.
Lutgen V, Kong L, Kau K, Madayag A, Mantsch J, Baker D
Addict Biol
. 2012 Sep;
19(4):529-38.
PMID: 22970924
Factors that result in augmented reinstatement, including increased withdrawal period duration and high levels of cocaine consumption, may provide insight into relapse vulnerability. The neural basis of augmented reinstatement may...
10.
Bridges R, Lutgen V, Lobner D, Baker D
Pharmacol Rev
. 2012 Jul;
64(3):780-802.
PMID: 22759795
System x(c)(-) represents an intriguing target in attempts to understand the pathological states of the central nervous system. Also called a cystine-glutamate antiporter, system x(c)(-) typically functions by exchanging one...