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Victor Ona

Explore the profile of Victor Ona including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 572
Followers 0
Related Specialties
Pharmacology
Rheumatology
General Medicine
Top 10 Co-Authors
Silvestru-Alexandru Big
Margaret K Moseley
Kosalaram Goteti
Seth Levin
Bogdan-Ovidiu Feciche
Hans Guehring
Indrani Nandy
Flavie Moreau
Rakesh Jain
Asger Reinstrup Bihlet
Published In
Nature
Rheumatology (Oxford)
ACR Open Rheumatol
Clin Pract
Am J Respir Crit Care Med
Affiliations
Soon will be listed here.
Recent Articles
1.
Posterior Retroperitoneoscopic Bilateral Adrenalectomy: A New Standard for Bilateral Pheochromocytoma? (with video)
Feciche B, Big S, Mirt S, Ona V, Barbos V
Chirurgia (Bucur) . 2025 Mar; 120(1):125-126. PMID: 40051325
video width="640" height="480" controls controlsList="nodownload" poster="https://www.revistachirurgia.ro/pdfs/video/posterior_retroperitoneoscopic_bilateral_adrenalectomy.jpg" style="margin-top: -20px;" source src="https://www.revistachirurgia.ro/pdfs/video/posterior_retroperitoneoscopic_bilateral_adrenalectomy.mov" type="video/mp4" Your browser does not support the video tag. /video Bilateral adrenal involvement occurs in about 20% of pheochromocytomas, more...
2.
Extraperitoneal Open Radical Cystectomy: A New Standard in Frail Patients with Muscle-Invasive Bladder Cancer?
Porav-Hodade D, Big S, Barbos V, Gherle B, Jerzicska E, Ona V, et al.
Clin Pract . 2024 Nov; 14(6):2559-2567. PMID: 39585029
: Radical cystectomy (RC) represents one of the most complex and morbid surgical procedures in the field of Urology. Extraperitoneal open RC has emerged as an alternative to the traditional...
3.
Cognitive effects, pharmacokinetics, and safety of zuranolone administered alone or with alprazolam or ethanol in healthy adults in a phase 1 trial
Dunbar J, Walling D, Hassman H, Jain R, Czysz A, Nandy I, et al.
J Psychopharmacol . 2024 Oct; 38(12):1122-1136. PMID: 39394685
Background: Zuranolone is an oral, once-daily, 14-day treatment course approved for adults with postpartum depression in the United States. Aims: To assess cognitive effects, pharmacokinetics, and safety of zuranolone, alone...
4.
Effects of zuranolone on next-day simulated driving in healthy adults
Dunbar J, Morelli G, Jain R, Vaudreuil C, Nandy I, Ona V, et al.
Psychopharmacology (Berl) . 2024 Sep; 242(2):389-400. PMID: 39302437
Rationale: Zuranolone is an oral positive allosteric modulator of GABA receptors. Due to its central nervous system (CNS) activity, zuranolone may impact activities requiring complex cognition, including driving. Objective: Evaluate...
5.
Safety, Tolerability, and Pharmacodynamics of the ADAMTS-5 Nanobody M6495: Two Phase 1, Single-Center, Double-Blind, Randomized, Placebo-Controlled Studies in Healthy Subjects and Patients With Osteoarthritis
Bihlet A, Balchen T, Goteti K, Sonne J, Ladel C, Karsdal M, et al.
ACR Open Rheumatol . 2024 Feb; 6(4):205-213. PMID: 38311369
Objective: To assess the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of single and multiple injections of M6495, a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)  nanobody, in healthy volunteers...
6.
Phase 1 study in healthy participants of the safety, pharmacokinetics, and pharmacodynamics of enpatoran (M5049), a dual antagonist of toll-like receptors 7 and 8
Port A, Shaw J, Klopp-Schulze L, Bytyqi A, Vetter C, Hussey E, et al.
Pharmacol Res Perspect . 2021 Aug; 9(5):e00842. PMID: 34414672
This study evaluated the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single and multiple oral doses of enpatoran (formerly named M5049), a new toll-like receptor (TLR) 7 and 8...
7.
Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study
Eckstein F, Hochberg M, Guehring H, Moreau F, Ona V, Bihlet A, et al.
Ann Rheum Dis . 2021 May; 80(8):1062-1069. PMID: 33962962
Objective: The FORWARD (FGF-18 Osteoarthritis Randomized Trial with Administration of Repeated Doses) trial assessed efficacy and safety of the potential disease-modifying osteoarthritis drug (DMOAD) sprifermin in patients with knee osteoarthritis....
8.
Safety and clinical activity of atacicept in the long-term extension of the phase 2b ADDRESS II study in systemic lupus erythematosus
Wallace D, Isenberg D, Morand E, Vazquez-Mateo C, Kao A, Aydemir A, et al.
Rheumatology (Oxford) . 2021 Feb; 60(11):5379-5389. PMID: 33547784
Objectives: Atacicept reduced SLE disease activity in the phase 2b ADDRESS II study, particularly in patients with high disease activity (HDA; SLEDAI-2K ≥10) at screening. We assessed long-term safety and...
9.
Adenocarcinoma of the right colon penetrating the liver
Bartos A, Bartos D, Ona V, Acalovschi I, Iancu C
J Gastrointestin Liver Dis . 2014 Apr; 23(1):10. PMID: 24689089
No abstract available.
10.
Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation
Horan G, Wood S, Ona V, Li D, Lukashev M, Weinreb P, et al.
Am J Respir Crit Care Med . 2007 Oct; 177(1):56-65. PMID: 17916809
Rationale: Transforming growth factor (TGF)-beta has a central role in driving many of the pathological processes that characterize pulmonary fibrosis. Inhibition of the integrin alpha(v)beta6, a key activator of TGF-beta...