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Victor L Jensen

Explore the profile of Victor L Jensen including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 509
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Recent Articles
1.
Romeggio F, Bischoff R, Moller C, Jensen V, Gioria E, Egeberg Tankard R, et al.
ACS Omega . 2024 Dec; 9(50):49759-49766. PMID: 39713667
Magnetron sputtering is a versatile method for investigating model system catalysts thanks to its simplicity, reproducibility, and chemical-free synthesis process. It has recently emerged as a promising technique for synthesizing...
2.
van Dam T, Kennedy J, van der Lee R, de Vrieze E, Wunderlich K, Rix S, et al.
PLoS One . 2019 May; 14(5):e0216705. PMID: 31095607
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic diseases collectively called ciliopathies. The current rate at which new...
3.
Jensen V, Lambacher N, Li C, Mohan S, Williams C, Inglis P, et al.
EMBO Rep . 2018 Nov; 19(12). PMID: 30429209
Genetic disorders caused by cilia dysfunction, termed ciliopathies, frequently involve the intraflagellar transport (IFT) system. Mutations in IFT subunits-including IFT-dynein motor DYNC2H1-impair ciliary structures and Hedgehog signalling, typically leading to...
4.
Jensen V, Leroux M
Curr Opin Cell Biol . 2017 Apr; 47:83-91. PMID: 28432921
Primary cilia are microtubule-based organelles found on most mammalian cell surfaces. They possess a soluble matrix and membrane contiguous with the cell body cytosol and plasma membrane, and yet, have...
5.
Jensen V, Carter S, Sanders A, Li C, Kennedy J, Timbers T, et al.
PLoS Genet . 2016 Dec; 12(12):e1006469. PMID: 27930654
Primary cilia are specialised sensory and developmental signalling devices extending from the surface of most eukaryotic cells. Defects in these organelles cause inherited human disorders (ciliopathies) such as retinitis pigmentosa...
6.
Li C, Jensen V, Park K, Kennedy J, Garcia-Gonzalo F, Romani M, et al.
PLoS Biol . 2016 Mar; 14(3):e1002416. PMID: 26982032
Cilia have a unique diffusion barrier ("gate") within their proximal region, termed transition zone (TZ), that compartmentalises signalling proteins within the organelle. The TZ is known to harbour two functional...
7.
Jensen V, Li C, Bowie R, Clarke L, Mohan S, Blacque O, et al.
EMBO J . 2015 Sep; 34(20):2537-56. PMID: 26392567
Cilia are thought to harbour a membrane diffusion barrier within their transition zone (TZ) that compartmentalises signalling proteins. How this "ciliary gate" assembles and functions remains largely unknown. Contrary to...
8.
Molnar A, Yuen D, Tangri N, Jensen V
Can J Kidney Health Dis . 2015 Mar; 1:18. PMID: 25780610
Purpose Of Review: Chronic kidney disease affects approximately 3 million Canadians. Ongoing investment in high quality kidney research is needed to improve the care of patients with kidney disease. The...
9.
Huang L, Szymanska K, Jensen V, Janecke A, Innes A, Davis E, et al.
Am J Hum Genet . 2011 Dec; 89(6):713-30. PMID: 22152675
Joubert syndrome related disorders (JSRDs) have broad but variable phenotypic overlap with other ciliopathies. The molecular etiology of this overlap is unclear but probably arises from disrupting common functional module...
10.
Jensen V, Simonsen K, Lee Y, Park D, Riddle D
PLoS One . 2011 Jan; 5(12):e15902. PMID: 21209831
The DAF-16/FOXO transcription factor is the major downstream output of the insulin/IGF1R signaling pathway controlling C. elegans dauer larva development and aging. To identify novel downstream genes affecting dauer formation,...