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Victor J B van Santen

Explore the profile of Victor J B van Santen including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
van Santen V, Jin J, Hogervorst J, Bakker A
Biochem Biophys Res Commun . 2023 Jan; 646:70-77. PMID: 36706708
Once prostate cancer (PC) metastasizes towards bone the 5-year survival rates drop with 70%, but it is largely unknown why. Bone is continuously mechanically loaded, which likely modulates the paracrine...
2.
van Santen V, Doulabi B, Semeins C, Hogervorst J, Bratengeier C, Bakker A
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36614201
Once prostate cancer cells metastasize to bone, they perceive approximately 2 kPa compression. We hypothesize that 2 kPa compression stimulates the epithelial-to-mesenchymal transition (EMT) of prostate cancer cells and alters...
3.
van Santen V, Bastidas Coral A, Hogervorst J, Klein-Nulend J, Bakker A
Biomolecules . 2022 Feb; 12(2). PMID: 35204670
Standard cell cultures may not predict the proliferation and differentiation potential of human mesenchymal stromal cells (MSCs) after seeding on a scaffold and implanting this construct in a bone defect....
4.
van Santen V, Klein-Nulend J, Bakker A, Jaspers R
Cell Biochem Biophys . 2022 Jan; 80(1):161-170. PMID: 35067867
During myofiber regeneration, myoblasts are continuously subjected to shear stress. It is currently not known whether shear stress affects the regenerative capacity of myoblasts when extracellular matrix (ECM) stiffness increases...