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Victor G Levitsky

Explore the profile of Victor G Levitsky including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Levitsky V, Raditsa V, Tsukanov A, Mukhin A, Zhimulev I, Merkulova T
Int J Mol Sci . 2025 Jan; 26(1. PMID: 39796242
Transcription factors (TFs) are the main regulators of eukaryotic gene expression. The cooperative binding of at least two TFs to genomic DNA is a major mechanism of transcription regulation. Massive...
2.
Raditsa V, Tsukanov A, Bogomolov A, Levitsky V
NAR Genom Bioinform . 2024 Jul; 6(3):lqae090. PMID: 39071850
Efficient motif discovery from the results of wide-genome mapping of transcription factor binding sites (ChIP-seq) is dependent on the choice of background nucleotide sequences. The foreground sequences (ChIP-seq peaks) represent...
3.
Oshchepkov D, Chadaeva I, Kozhemyakina R, Shikhevich S, Sharypova E, Savinkova L, et al.
Int J Mol Sci . 2022 Oct; 23(20). PMID: 36293128
Studies on hereditary fixation of the tame-behavior phenotype during animal domestication remain relevant and important because they are of both basic research and applied significance. In model animals, gray rats...
4.
Lavrekha V, Levitsky V, Tsukanov A, Bogomolov A, Grigorovich D, Omelyanchuk N, et al.
Front Plant Sci . 2022 Sep; 13:942710. PMID: 36061801
Having DNA-binding profiles for a sufficient number of genome-encoded transcription factors (TFs) opens up the perspectives for systematic evaluation of the upstream regulators for the gene lists. Plant Cistrome database,...
5.
Levitsky V, Mukhin A, Oshchepkov D, Zemlyanskaya E, Lashin S
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012247
(1) Background: The widespread application of ChIP-seq technology requires annotation of cis-regulatory modules through the search of co-occurred motifs. (2) Methods: We present the web server Motifs Co-Occurrence Tool (Web-MCOT)...
6.
Tsukanov A, Mironova V, Levitsky V
Front Plant Sci . 2022 Aug; 13:938545. PMID: 35968123
Position weight matrix (PWM) is the traditional motif model representing the transcription factor (TF) binding sites. It proposes that the positions contribute independently to TFs binding affinity, although this hypothesis...
7.
Zemlyanskaya E, Dolgikh V, Levitsky V, Mironova V
Curr Opin Plant Biol . 2021 Jun; 63:102058. PMID: 34098218
Innovative omics technologies, advanced bioinformatics, and machine learning methods are rapidly becoming integral tools for plant functional genomics, with tremendous recent advances made in this field. In transcriptional regulation, an...
8.
Levitsky V, Zykova T, Moshkin Y, Zhimulev I
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33291385
We analyzed the whole-genome experimental maps of nucleosomes in and classified genes by the expression level in S2 cells (RPKM value, reads per kilobase million) as well as the number...
9.
Khoroshko V, Pokholkova G, Levitsky V, Zykova T, Antonenko O, Belyaeva E, et al.
Genes (Basel) . 2020 Apr; 11(4). PMID: 32290448
The polytene chromosomes are the best model for studying the genome organization during interphase. Despite of the long-term studies available on genetic organization of polytene chromosome bands and interbands, little...
10.
Demakova O, Demakov S, Boldyreva L, Zykova T, Levitsky V, Semeshin V, et al.
Chromosoma . 2019 Dec; 129(1):25-44. PMID: 31820086
In Drosophila melanogaster, the chromatin of interphase polytene chromosomes appears as alternating decondensed interbands and dense black or thin gray bands. Recently, we uncovered four principle chromatin states (4НММ model)...